Abstract
The last decade has witnessed significant advances in the adoptive cell transfer (ACT) technique, which has been appreciated as one of the most promising treatments for patients with cancer. Utilization of ACT can enhance the function of the immune system or improve the specificity and persistence of transferred cells. Various immune cells including T lymphocytes, natural killer cells, dendritic cells, and even stem cells can be used in the ACT despite their different functional mechanisms. Colorectal cancer (CRC) is among the most common malignancies and causes millions of deaths worldwide every year. In this review, we discuss the status and perspective of the ACT in the treatment of CRC.
| Original language | English |
|---|---|
| Pages (from-to) | 5784-5800 |
| Number of pages | 17 |
| Journal | Theranostics |
| Volume | 8 |
| Issue number | 20 |
| DOIs | |
| State | Published - 2018 |
Bibliographical note
Publisher Copyright:© Ivyspring International Publisher.
Funding
This study was supported by a grant from the National Natural Science Foundation of China (No. 81573751).
| Funders | Funder number |
|---|---|
| National Institute of Allergy and Infectious Diseases | R01AI121180 |
| National Natural Science Foundation of China (NSFC) | 81573751 |
Keywords
- Adoptive cell transfer
- Colorectal cancer
- Immunotherapy
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
