Abstract
This chapter presents the traditional categories of overview, etiology/pathophysiology, signalment/history, clinical features, key differential diagnosis, diagnostics, and therapeutics of aflatoxins in equine. Aflatoxin B1 is most toxic and is usually present in the highest concentrations in feedstuffs. Aflatoxins can cause acute or chronic liver disease, depending on the dosage and duration of ingestion. The toxic metabolites of aflatoxins are reactive epoxides, which cause hepatocellular dysfunction and necrosis, bile duct hyperplasia, and, in chronic cases, hepatic fibrosis. The chapter is an indispensable reference for veterinary clinicians and students dealing with equine medicine, as well as for anyone seeking concise and comprehensive information about equine toxicology.
| Original language | English |
|---|---|
| Title of host publication | Blackwell's Five-Minute Veterinary Consult Clinical Companion |
| Subtitle of host publication | Equine Toxicology |
| Pages | 213-219 |
| Number of pages | 7 |
| ISBN (Electronic) | 9781119671527 |
| DOIs | |
| State | Published - Jan 1 2021 |
Bibliographical note
Publisher Copyright:© 2022 John Wiley and Sons, Inc. All rights reserved.
Keywords
- aflatoxins
- equine medicine
- equine toxicology
- hepatocellular dysfunction
- veterinary clinicians
ASJC Scopus subject areas
- General Veterinary