African American race is associated with poorer outcomes in heart failure patients

Kelly L. Wierenga; Rebecca L. Dekker; Terry A. Lennie; Misook L. Chung; Kathleen Dracup

doi:10.1177/0193945916661277

African American race is associated with poorer outcomes in heart failure patients

Kelly L. Wierenga, Rebecca L. Dekker, Terry A. Lennie, Misook L. Chung, Kathleen Dracup

College of Nursing

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Health care disparities associated with African American race may influence event-free survival in patients with heart failure (HF). A secondary data analysis included 863 outpatients enrolled in a multicenter HF registry. Cox regression was used to determine whether African American race was associated with shorter HF event-free survival after controlling for covariates. The multivariable-adjusted hazard ratios (95% confidence intervals [CI]) of older age (1.03, 95% CI = [1.01, 1.04]), New York Heart Association (NYHA) functional class (1.73, 95% CI = [1.29, 2.31]), depressive symptoms (1.05, 95% CI = [1.02, 1.07]), and African American race (1.64, 95% CI = [1.01, 2.68]) were predictors of shorter event-free survival (all ps <.05). Comparisons showed that NYHA functional class was predictive of shorter event-free survival in Caucasians (1.81, 95% CI = [1.33, 2.46]) but not in African Americans (1.24, 95% CI = [.40, 3.81]). African Americans with HF experienced a disparate risk of shorter eventfree survival not explained by a variety of risk factors.

Original language	English
Pages (from-to)	524-538
Number of pages	15
Journal	Western Journal of Nursing Research
Volume	39
Issue number	4
DOIs	https://doi.org/10.1177/0193945916661277
State	Published - Apr 2017

Bibliographical note

Publisher Copyright:
© The Author(s) 2016.

Funding

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This project was funded by the National Institutes of Health (NIH), National Institute of Nursing Research, R01 NR008567; NIH, National Heart Lung and Blood Institute, 5R01HL083176-5; NIH, National Institute of Nursing Research, 1P20NR010679; and training grants from the NIH (National Institute of Nursing Research K23 NR013480 and 1F31 NR014754); Sigma Theta Tau Alpha Psi; Blue Cross and Blue Shield of Michigan Foundation; and the Jonas Center for Nursing Excellence.

Funders	Funder number
Jonas Center for Nursing Excellence
Michigan State University Foundation
Sigma Theta Tau Alpha Psi
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)	1F31 NR014754, 5R01HL083176-5, 1P20NR010679
National Institute of Health National Institute of Nursing Research	K23NR013480, R01 NR008567

Keywords

Health disparities
Heart failure
Race

ASJC Scopus subject areas

General Nursing

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10.1177/0193945916661277

Cite this

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title = "African American race is associated with poorer outcomes in heart failure patients",

abstract = "Health care disparities associated with African American race may influence event-free survival in patients with heart failure (HF). A secondary data analysis included 863 outpatients enrolled in a multicenter HF registry. Cox regression was used to determine whether African American race was associated with shorter HF event-free survival after controlling for covariates. The multivariable-adjusted hazard ratios (95\% confidence intervals [CI]) of older age (1.03, 95\% CI = [1.01, 1.04]), New York Heart Association (NYHA) functional class (1.73, 95\% CI = [1.29, 2.31]), depressive symptoms (1.05, 95\% CI = [1.02, 1.07]), and African American race (1.64, 95\% CI = [1.01, 2.68]) were predictors of shorter event-free survival (all ps <.05). Comparisons showed that NYHA functional class was predictive of shorter event-free survival in Caucasians (1.81, 95\% CI = [1.33, 2.46]) but not in African Americans (1.24, 95\% CI = [.40, 3.81]). African Americans with HF experienced a disparate risk of shorter eventfree survival not explained by a variety of risk factors.",

keywords = "Health disparities, Heart failure, Race",

author = "Wierenga, \{Kelly L.\} and Dekker, \{Rebecca L.\} and Lennie, \{Terry A.\} and Chung, \{Misook L.\} and Kathleen Dracup",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2016.",

year = "2017",

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doi = "10.1177/0193945916661277",

language = "English",

volume = "39",

pages = "524--538",

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T1 - African American race is associated with poorer outcomes in heart failure patients

AU - Wierenga, Kelly L.

AU - Dekker, Rebecca L.

AU - Lennie, Terry A.

AU - Chung, Misook L.

AU - Dracup, Kathleen

N1 - Publisher Copyright: © The Author(s) 2016.

PY - 2017/4

Y1 - 2017/4

N2 - Health care disparities associated with African American race may influence event-free survival in patients with heart failure (HF). A secondary data analysis included 863 outpatients enrolled in a multicenter HF registry. Cox regression was used to determine whether African American race was associated with shorter HF event-free survival after controlling for covariates. The multivariable-adjusted hazard ratios (95% confidence intervals [CI]) of older age (1.03, 95% CI = [1.01, 1.04]), New York Heart Association (NYHA) functional class (1.73, 95% CI = [1.29, 2.31]), depressive symptoms (1.05, 95% CI = [1.02, 1.07]), and African American race (1.64, 95% CI = [1.01, 2.68]) were predictors of shorter event-free survival (all ps <.05). Comparisons showed that NYHA functional class was predictive of shorter event-free survival in Caucasians (1.81, 95% CI = [1.33, 2.46]) but not in African Americans (1.24, 95% CI = [.40, 3.81]). African Americans with HF experienced a disparate risk of shorter eventfree survival not explained by a variety of risk factors.

AB - Health care disparities associated with African American race may influence event-free survival in patients with heart failure (HF). A secondary data analysis included 863 outpatients enrolled in a multicenter HF registry. Cox regression was used to determine whether African American race was associated with shorter HF event-free survival after controlling for covariates. The multivariable-adjusted hazard ratios (95% confidence intervals [CI]) of older age (1.03, 95% CI = [1.01, 1.04]), New York Heart Association (NYHA) functional class (1.73, 95% CI = [1.29, 2.31]), depressive symptoms (1.05, 95% CI = [1.02, 1.07]), and African American race (1.64, 95% CI = [1.01, 2.68]) were predictors of shorter event-free survival (all ps <.05). Comparisons showed that NYHA functional class was predictive of shorter event-free survival in Caucasians (1.81, 95% CI = [1.33, 2.46]) but not in African Americans (1.24, 95% CI = [.40, 3.81]). African Americans with HF experienced a disparate risk of shorter eventfree survival not explained by a variety of risk factors.

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African American race is associated with poorer outcomes in heart failure patients

Abstract

Bibliographical note

Funding

Keywords

ASJC Scopus subject areas

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