Alkyl-alkenyl cross coupling via alkyl cobaloxime radical chemistry.An alkyl equivalent to the heck reaction compatible with common organic functional groups

Bruce P. Branchaud, Mark S. Meier, Youngshin Choi

Research output: Contribution to journalArticlepeer-review

73 Scopus citations

Abstract

A novel cobalt-mediated radical-olefin coupling reaction is described which regenerates the olefin functionality in the final product. The regeneration of olefin functionality is unique among radical-olefin couplings using simple activated alkenes.

Original languageEnglish
Pages (from-to)167-170
Number of pages4
JournalTetrahedron Letters
Volume29
Issue number2
DOIs
StatePublished - 1988

Bibliographical note

Funding Information:
Acknowledgements. We acknowledge the financial assistance of the University of Oregon, NIH BRS 2 SO7 RR07080, an M. J. Murdoch Charitable Trust Grant of the Research Corporation, and the donors of the Petroleum Research Fund, administered by the America1 Chemical Society. The General Electric BE-300 NMR spectrometer used in this work was purchased with funds provided by PHS RR 02336 and NSF CHE 9411177.

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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