Alternative splicing in plant immunity

Shengming Yang, Fang Tang, Hongyan Zhu

Research output: Contribution to journalReview articlepeer-review

80 Scopus citations

Abstract

Alternative splicing (AS) occurs widely in plants and can provide the main source of transcriptome and proteome diversity in an organism. AS functions in a range of physiological processes, including plant disease resistance, but its biological roles and functional mechanisms remain poorly understood. Many plant disease resistance (R) genes undergo AS, and several R genes require alternatively spliced transcripts to produce R proteins that can specifically recognize pathogen invasion. In the finely-tuned process of R protein activation, the truncated isoforms generated by AS may participate in plant disease resistance either by suppressing the negative regulation of initiation of immunity, or by directly engaging in effector-triggered signaling. Although emerging research has shown the functional significance of AS in plant biotic stress responses, many aspects of this topic remain to be understood. Several interesting issues surrounding the AS of R genes, especially regarding its functional roles and regulation, will require innovative techniques and additional research to unravel.

Original languageEnglish
Pages (from-to)10424-10445
Number of pages22
JournalInternational Journal of Molecular Sciences
Volume15
Issue number6
DOIs
StatePublished - Jun 10 2014

Keywords

  • Alternative splicing
  • CC-NBS-LRR
  • Disease resistance
  • Post-transcriptional regulation
  • RNA processing
  • TIR-NBS-LRR

ASJC Scopus subject areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Fingerprint

Dive into the research topics of 'Alternative splicing in plant immunity'. Together they form a unique fingerprint.

Cite this