Ambulatory venovenous extracorporeal respiratory support as a bridge for cystic fibrosis patients to emergent lung transplantation

Don Hayes, Jasleen Kukreja, Joseph D. Tobias, Hubert O. Ballard, Charles W. Hoopes

Research output: Contribution to journalArticlepeer-review

73 Scopus citations

Abstract

Venovenous extracorporeal membrane oxygenation (VV ECMO) is a therapeutic option to bridge patients with advanced lung disease to lung transplantation. The use of VV ECMO avoids the use of mechanical ventilation while allowing patients to participate in physical therapy and to eat normally while receiving respiratory support. We describe the successful use of ambulatory single-venous VV ECMO as a bridge to bilateral lung transplantation in 4 patients with end-stage lung disease due to cystic fibrosis who developed acute hypercapnic respiratory failure. The use of ambulatory single-venous VV ECMO was safe and effective in this small cohort of CF patients. Based on our experiences, our belief is that a key step in the treatment course was early application of VV ECMO soon after development of acute respiratory failure requiring mechanical ventilation.

Original languageEnglish
Pages (from-to)40-45
Number of pages6
JournalJournal of Cystic Fibrosis
Volume11
Issue number1
DOIs
StatePublished - Jan 2012

Keywords

  • Ambulatory
  • Bridge
  • Cystic fibrosis
  • Extracorporeal membrane oxygenation
  • Lung transplantation
  • Venovenous

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

Fingerprint

Dive into the research topics of 'Ambulatory venovenous extracorporeal respiratory support as a bridge for cystic fibrosis patients to emergent lung transplantation'. Together they form a unique fingerprint.

Cite this