TY - JOUR
T1 - Ambulatory venovenous extracorporeal respiratory support as a bridge for cystic fibrosis patients to emergent lung transplantation
AU - Hayes, Don
AU - Kukreja, Jasleen
AU - Tobias, Joseph D.
AU - Ballard, Hubert O.
AU - Hoopes, Charles W.
PY - 2012/1
Y1 - 2012/1
N2 - Venovenous extracorporeal membrane oxygenation (VV ECMO) is a therapeutic option to bridge patients with advanced lung disease to lung transplantation. The use of VV ECMO avoids the use of mechanical ventilation while allowing patients to participate in physical therapy and to eat normally while receiving respiratory support. We describe the successful use of ambulatory single-venous VV ECMO as a bridge to bilateral lung transplantation in 4 patients with end-stage lung disease due to cystic fibrosis who developed acute hypercapnic respiratory failure. The use of ambulatory single-venous VV ECMO was safe and effective in this small cohort of CF patients. Based on our experiences, our belief is that a key step in the treatment course was early application of VV ECMO soon after development of acute respiratory failure requiring mechanical ventilation.
AB - Venovenous extracorporeal membrane oxygenation (VV ECMO) is a therapeutic option to bridge patients with advanced lung disease to lung transplantation. The use of VV ECMO avoids the use of mechanical ventilation while allowing patients to participate in physical therapy and to eat normally while receiving respiratory support. We describe the successful use of ambulatory single-venous VV ECMO as a bridge to bilateral lung transplantation in 4 patients with end-stage lung disease due to cystic fibrosis who developed acute hypercapnic respiratory failure. The use of ambulatory single-venous VV ECMO was safe and effective in this small cohort of CF patients. Based on our experiences, our belief is that a key step in the treatment course was early application of VV ECMO soon after development of acute respiratory failure requiring mechanical ventilation.
KW - Ambulatory
KW - Bridge
KW - Cystic fibrosis
KW - Extracorporeal membrane oxygenation
KW - Lung transplantation
KW - Venovenous
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U2 - 10.1016/j.jcf.2011.07.009
DO - 10.1016/j.jcf.2011.07.009
M3 - Article
C2 - 22035707
AN - SCOPUS:84855899456
SN - 1569-1993
VL - 11
SP - 40
EP - 45
JO - Journal of Cystic Fibrosis
JF - Journal of Cystic Fibrosis
IS - 1
ER -