American College of Gastroenterology Guidelines: Management of Acute Pancreatitis

Scott Tenner, Santhi Swaroop Vege, Sunil G. Sheth, Bryan Sauer, Allison Yang, Darwin L. Conwell, Rena H. Yadlapati, Timothy B. Gardner

Research output: Contribution to journalArticlepeer-review


Acute pancreatitis (AP), defined as acute inflammation of the pancreas, is one of the most common diseases of the gastrointestinal tract leading to hospital admission in the United States. It is important for clinicians to appreciate that AP is heterogenous, progressing differently among patients and is often unpredictable. While most patients experience symptoms lasting a few days, almost one-fifth of patients will go on to experience complications, including pancreatic necrosis and/or organ failure, at times requiring prolonged hospitalization, intensive care, and radiologic, surgical, and/or endoscopic intervention. Early management is essential to identify and treat patients with AP to prevent complications. Patients with biliary pancreatitis typically will require surgery to prevent recurrent disease and may need early endoscopic retrograde cholangiopancreatography if the disease is complicated by cholangitis. Nutrition plays an important role in treating patients with AP. The safety of early refeeding and importance in preventing complications from AP are addressed. This guideline will provide an evidence-based practical approach to the management of patients with AP.

Original languageEnglish
Pages (from-to)419-437
Number of pages19
JournalAmerican Journal of Gastroenterology
Issue number3
StatePublished - Mar 1 2024

Bibliographical note

Publisher Copyright:
© 2024 by The American College of Gastroenterology.

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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