Amyloid β-peptide(1-42), oxidative stress, and alzheimer's disease

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations


Alzheimer's disease (AD) a progressive, age-related neurodegenerative disorder that affects memory, cognition, and speech, is present in more than 4 million persons. The number of cases of AD will significantly elevate, because the mean population in the United States is increasing [1]. AD is characterized pathologically by the presence of extracellular senile plaques, intracellular neurofibrillary tangles, and synapse loss. Senile plaques are composed of an amyloid beta-peptide (Aβ) core surrounded by dystrophic neurites.

Original languageEnglish
Title of host publicationAbeta Peptide and Alzheimer's Disease
Subtitle of host publicationCelebrating a Century of Research
Number of pages10
StatePublished - 2007

ASJC Scopus subject areas

  • Medicine (all)


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