An automated movement assessment panel for upper limb motor functions in rhesus monkeys and humans

Don M. Gash, Zhiming Zhang, Gloria Umberger, Kim Mahood, Melody Smith, Charles Smith, Greg A. Gerhardt

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


As part of our studies of age-associated changes in motor functions, we have designed an automated movement assessment panel (MAP) to evaluate upper limb and hand movements. Here we describe two versions of the MAP, one for human testing and one for nonhuman primates, and methods for conducting parallel tests in rhesus monkeys and human volunteers. The results are reported from a battery of tests on young adult rhesus monkeys (n=10, 5-8 years old), young adult human subjects (n=10, 18-22 years old) and ten aged human subjects (n=10, 66-68 years old) to demonstrate the capability of the MAP in quantifying arm and hand movement times. The performance times on the two simplest tasks tested were consistent from trial to trial, demonstrating that a stable behavioral baseline could be established for evaluating changes in motor functions over time and assessing treatments for improving motor functions. Motor learning was seen in the more complex movement tasks tested, indicating their usefulness in analyzing this behavior. Finally, age-associated changes in performance times were robustly delineated by the four tasks evaluated in the human subjects. Copyright (C) 1999 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)111-117
Number of pages7
JournalJournal of Neuroscience Methods
Issue number2
StatePublished - Jul 15 1999

Bibliographical note

Funding Information:
We wish to thank Robert Fox, Erin Manning and Dr Calum Avison for assistance with preliminary tests of the panel. We also thank Dr Richard Kryscio for his assistance with statistical analysis of the data. This study was supported by NIH Grants NS35642, MH01245, AG06434 and AG13494.


  • Aging
  • Fine motor movements
  • Hand
  • Human
  • Rhesus monkeys
  • Testing

ASJC Scopus subject areas

  • Neuroscience (all)


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