An experimental test of question framing in health state utility assessment

Karen Blumenschein, Magnus Johannesson

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


In the standard gamble and time trade-off methods of health state utility assessment, a specified health state and an alternative are compared. This alternative can be framed in terms of a loss or a gain in reference to the first health state. In this paper, we test whether this framing affects the estimated health state utilities. The experiment was carried out on a group of pharmacy students, randomly divided between the loss or gain version (n=182). The null hypothesis of no difference between the loss and gain versions is rejected for the standard gamble method, but not for the time trade-off method. Copyright (C) 1998 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)187-193
Number of pages7
JournalHealth Policy
Issue number3
StatePublished - Sep 1998

Bibliographical note

Funding Information:
The authors thank an anonymous referee for helpful comments. KB was supported in part by the Pharmaceutical Research and Manufacturers of America Foundation Faculty Development Award in Pharmacoeconomics.


  • Cost-utility analysis
  • Framing
  • Loss aversion
  • QALYs
  • Standard gamble
  • Time trade-off

ASJC Scopus subject areas

  • Health Policy


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