An investigation of digital signal processing for shaped pulses for all-digital PET

Qingguo Xie, Jun Zhu, Xi Wang, Bo Zhang, Caigang Zhu, Ning Guo, Zhi Zhang, Chin Tu Chen, Yau W. Wah, Mircea Bogdan, Chien Min Kao

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations


We present our work toward implementing all-digital signal processing for Positron Emission Tomography (PET) event detection. In the conventional PET system, proper calibration and extending event processing axe challenging tasks due to the huge number of channels and multiplexing of input signals in the mixed-signal front-end. To alleviate such limitations, we have proposed a simple all-digital PET system utilizing digital signal processing (DSP) technologies for analyzing event pulses generated in PET. In this work, we implement a Gaussian shaper circuit for scintillation pulses, which followed by a moderate sampling rate Analog-to-Digital Converter (ADC). We also evaluate two DSP algorithms for extracting time information from the digitized pulse samples, and the two algorithms examined could generate a coincidence timing resolution of ∼2.4ns FWHM, by using a 125MSps sampling rate ADC.

Original languageEnglish
Title of host publicationMedical Imaging 2008 - Physics of Medical Imaging
StatePublished - 2008
EventMedical Imaging 2008 - Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 18 2008Feb 21 2008

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceMedical Imaging 2008 - Physics of Medical Imaging
Country/TerritoryUnited States
CitySan Diego, CA


  • Fitting
  • Front-end electronics
  • Gaussian shaper
  • Positron emission tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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