TY - JOUR
T1 - An NMR-based metabolomic approach to assess metabolism in splanchnic tissues of steers
AU - Bertram, H. C.
AU - Kristensen, N. B.
AU - Malmendal, A.
AU - Nielsen, N. C.
AU - Jensen, S. K.
AU - Harmon, D. L.
PY - 2004
Y1 - 2004
N2 - 1H NMR spectra were acquired on plasma samples obtained from the mesenteric artery, hepatic portal vein and the hepatic vein of steers (n = 6) to demonstrate a NMR-based metabolomic approach to study splanchnic metabolism. The metabolic differences between the different plasma samples (arterial, portal, hepatic) were examined by partial least square regressions (PLSR) on the obtained spectra. These analyses revealed spectral differences that could be ascribed to changes in the level of propionate, β-hydroxybutyrate, lactate, acetate, n-butyrate and glucose, which was supported by biochemical analyses.
AB - 1H NMR spectra were acquired on plasma samples obtained from the mesenteric artery, hepatic portal vein and the hepatic vein of steers (n = 6) to demonstrate a NMR-based metabolomic approach to study splanchnic metabolism. The metabolic differences between the different plasma samples (arterial, portal, hepatic) were examined by partial least square regressions (PLSR) on the obtained spectra. These analyses revealed spectral differences that could be ascribed to changes in the level of propionate, β-hydroxybutyrate, lactate, acetate, n-butyrate and glucose, which was supported by biochemical analyses.
KW - Metabolism
KW - Metabolomics
KW - NMR
KW - Plasma
KW - Splanchnic
KW - Steer
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U2 - 10.22358/jafs/73921/2004
DO - 10.22358/jafs/73921/2004
M3 - Article
AN - SCOPUS:6944223042
SN - 1230-1388
VL - 13
SP - 295
EP - 298
JO - Journal of Animal and Feed Sciences
JF - Journal of Animal and Feed Sciences
IS - SUPPL. 1
ER -