An update on Sarcocystis neurona infections in animals and equine protozoal myeloencephalitis (EPM)

J. P. Dubey; D. K. Howe; M. Furr; W. J. Saville; A. E. Marsh; S. M. Reed; M. E. Grigg

doi:10.1016/j.vetpar.2015.01.026

An update on Sarcocystis neurona infections in animals and equine protozoal myeloencephalitis (EPM)

J. P. Dubey
, D. K. Howe
, M. Furr
, W. J. Saville
, A. E. Marsh
, S. M. Reed
, M. E. Grigg

Research output: Contribution to journal › Review article › peer-review

94 Scopus citations

Abstract

Equine protozoal myeloencephalitis (EPM) is a serious disease of horses, and its management continues to be a challenge for veterinarians. The protozoan Sarcocystis neurona is most commonly associated with EPM. S. neurona has emerged as a common cause of mortality in marine mammals, especially sea otters (. Enhydra lutris). EPM-like illness has also been recorded in several other mammals, including domestic dogs and cats. This paper updates S. neurona and EPM information from the last 15 years on the advances regarding life cycle, molecular biology, epidemiology, clinical signs, diagnosis, treatment and control.

Original language	English
Pages (from-to)	1-42
Number of pages	42
Journal	Veterinary Parasitology
Volume	209
Issue number	1-2
DOIs	https://doi.org/10.1016/j.vetpar.2015.01.026
State	Published - Apr 15 2015

Bibliographical note

Publisher Copyright:
© 2015 Published by Elsevier B.V.

Funding

This research was partially funded by the NIAID/Division of Intramural Research to MEG. MEG is a scholar of the Integrated Microbial Biodiversity program of the Canadian Institute for Advanced Research (CIFAR). We are grateful for S.K. Verma and R. Calero-Bernal for their help with illustrations and to O.C.H. Kwok and Ana Beatriez Cassinelli for bibliography.

Funders

Funder number

National Institute of Allergy and Infectious F32-AI286447 Cydney N. Johnson Diseases National Institute of Allergy and Infectious R01AI168214 Jason W. Rosch Diseases National Institute of Allergy and Infectious P30 Cydney N. Johnson Diseases National Institute of Allergy and Infectious R00-AI166116 Christopher D. Radka Diseases National Institute of Allergy and Infectious T32-AI106700 Cydney N. Johnson Diseases National Institute of Allergy and Infectious R01AI192221 Jason W. Rosch Diseases National Inst...

ZIAAI001018

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 14 Life Below Water

Keywords

Epidemiology
Equine protozoal myeloencephalitis
Life cycle
Marine mammals
Prevention
Sarcocystis neurona

ASJC Scopus subject areas

Parasitology
General Veterinary

Access to Document

10.1016/j.vetpar.2015.01.026

Cite this

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abstract = "Equine protozoal myeloencephalitis (EPM) is a serious disease of horses, and its management continues to be a challenge for veterinarians. The protozoan Sarcocystis neurona is most commonly associated with EPM. S. neurona has emerged as a common cause of mortality in marine mammals, especially sea otters (. Enhydra lutris). EPM-like illness has also been recorded in several other mammals, including domestic dogs and cats. This paper updates S. neurona and EPM information from the last 15 years on the advances regarding life cycle, molecular biology, epidemiology, clinical signs, diagnosis, treatment and control.",

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AU - Saville, W. J.

AU - Marsh, A. E.

AU - Reed, S. M.

AU - Grigg, M. E.

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AB - Equine protozoal myeloencephalitis (EPM) is a serious disease of horses, and its management continues to be a challenge for veterinarians. The protozoan Sarcocystis neurona is most commonly associated with EPM. S. neurona has emerged as a common cause of mortality in marine mammals, especially sea otters (. Enhydra lutris). EPM-like illness has also been recorded in several other mammals, including domestic dogs and cats. This paper updates S. neurona and EPM information from the last 15 years on the advances regarding life cycle, molecular biology, epidemiology, clinical signs, diagnosis, treatment and control.

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An update on Sarcocystis neurona infections in animals and equine protozoal myeloencephalitis (EPM)

Abstract

Bibliographical note

Funding

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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