Analysis of the prevalence and onset of dysphonia and dysphagia symptoms in movement disorders at an academic medical center

Mary E. Finger, Lyndsay L. Madden, Ihtsham U. Haq, Christopher J. McLouth, Mustafa S. Siddiqui

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Voice and swallowing impairments are common in movement disorders, but their effect on patients’ quality of life is not well known. This study was conducted to determine the onset and prevalence of patient-reported dysphonia and dysphagia symptoms in Parkinson's disease (PD), dystonia, Atypical Parkinsonian Syndromes (APS), and Essential Tremor (ET). Patients referred to a movement disorders clinic in a tertiary care academic medical center completed validated voice and swallowing specific Quality of Life (QOL)questionnaires: Voice Handicap Index-10 (VHI-10)and Eating Assessment Tool-10 (EAT-10). Patient demographics and clinical data were also collected. Two hundred and sixty-eight patients (males = 150, females = 118)completed the questionnaires (n was PD = 103, APS = 30, ET = 56, dystonia = 32, other = 47). Prevalence of patient-reported dysphagia symptoms was significantly higher in APS (63%)than PD (26%), ET (25%), and dystonia (31%). Prevalence of patient-reported dysphonia symptoms was significantly lower in ET (14%)compared to PD (34%)and APS (43%). Disease duration was shorter in PD and APS compared to ET and dystonia (p < 0.05)before reporting clinically significant dysphonia and dysphagia symptoms indicating an earlier onset of these symptoms. There were significant positive correlations between VHI-10 and EAT-10 scores and disease severity, as indicated by Unified Parkinson's Disease motor scores (p < 0.0001)and modified Fahn-Tolosa-Marin Tremor Rating sub-scores (p = 0.0013). Patient-reported dysphonia and dysphagia symptoms were present in one fourth of patients with PD, ET, dystonia, and almost two thirds in APS. Patient-reported QOL measures, such as VHI-10 and EAT-10, can help screen movement disorder patients for dysphonia and dysphagia symptoms.

Original languageEnglish
Pages (from-to)111-115
Number of pages5
JournalJournal of Clinical Neuroscience
Volume64
DOIs
StatePublished - Jun 2019

Bibliographical note

Funding Information:
L.L.M. received statistical support through a grant from National Center for Advancing Translational Sciences (NCATS), National Institutes of Health , through Grant Award Number UL1TR001420 . This funding organization did not contribute to the design or conduct this study.

Publisher Copyright:
© 2019 Elsevier Ltd

Keywords

  • Atypical Parkinsonian Syndromes
  • Dysphagia
  • Dysphonia
  • Dystonia
  • Essential Tremor
  • Parkinson's disease
  • Patient-reported outcome measures

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Fingerprint

Dive into the research topics of 'Analysis of the prevalence and onset of dysphonia and dysphagia symptoms in movement disorders at an academic medical center'. Together they form a unique fingerprint.

Cite this