TY - JOUR
T1 - ANTERIOR CRUCIATE LIGAMENT SECTIONING ALTERS CENTER of PRESSURE WITHIN the TIBIOFEMORAL JOINT
T2 - AN in VITRO STUDY
AU - Noginova, Julia
AU - Hoch, Matthew C.
AU - Weinhandl, Joshua
AU - Bawab, Sebastian
AU - Ringleb, Stacie I.
N1 - Publisher Copyright:
© 2019 World Scientific Publishing Company.
PY - 2019/3/1
Y1 - 2019/3/1
N2 - Anterior cruciate ligament (ACL) injuries often lead to secondary injuries, joint degradation, and were linked to osteoarthritis. There is little known about how ACL rupture affects the loading and contact characteristics within the tibiofemoral joint. The objective of this study was to evaluate changes in tibiofemoral joint contact pressure and center of pressure (COP) during dynamic motion before and after ACL sectioning in vitro. Six intact cadaveric knees were manipulated through three full cycles of motion ranging from 30 to 120 of flexion in a custom-built device. A pressure sensor inserted in the tibiofemoral joint measured contact pressure of the medial and lateral compartments as well as COP characteristics of the whole joint before and after the ACL was sectioned. There was a significant decrease in lateral-compartment peak pressure, medial and lateral mean pressure, and total contact area after the ACL was sectioned. In both intact and ACL deficient knees, a posterior-lateral shift in COP was observed during flexion and a medial-anterior shift when returning to extension. Plotting the COP trajectory through the flexion-extension cycle resulted in a distinct hysteresis curve due to the viscoelastic soft tissue properties. Following sectioning, the COP trajectory had a diminished area compared to the intact condition. The diminished area of contact pressure may be more problematic than the overall magnitude when the integrity of the ACL is compromised. The centralized pressure distribution to a smaller surface area over time may cause focal damage to the cartilage leading to osteoarthritis.
AB - Anterior cruciate ligament (ACL) injuries often lead to secondary injuries, joint degradation, and were linked to osteoarthritis. There is little known about how ACL rupture affects the loading and contact characteristics within the tibiofemoral joint. The objective of this study was to evaluate changes in tibiofemoral joint contact pressure and center of pressure (COP) during dynamic motion before and after ACL sectioning in vitro. Six intact cadaveric knees were manipulated through three full cycles of motion ranging from 30 to 120 of flexion in a custom-built device. A pressure sensor inserted in the tibiofemoral joint measured contact pressure of the medial and lateral compartments as well as COP characteristics of the whole joint before and after the ACL was sectioned. There was a significant decrease in lateral-compartment peak pressure, medial and lateral mean pressure, and total contact area after the ACL was sectioned. In both intact and ACL deficient knees, a posterior-lateral shift in COP was observed during flexion and a medial-anterior shift when returning to extension. Plotting the COP trajectory through the flexion-extension cycle resulted in a distinct hysteresis curve due to the viscoelastic soft tissue properties. Following sectioning, the COP trajectory had a diminished area compared to the intact condition. The diminished area of contact pressure may be more problematic than the overall magnitude when the integrity of the ACL is compromised. The centralized pressure distribution to a smaller surface area over time may cause focal damage to the cartilage leading to osteoarthritis.
KW - ACL
KW - Biomechanics
KW - Loading
KW - Osteoarthritis
KW - Tibiofemoral
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U2 - 10.1142/S0218957719500015
DO - 10.1142/S0218957719500015
M3 - Article
AN - SCOPUS:85079789214
SN - 0218-9577
VL - 22
JO - Journal of Musculoskeletal Research
JF - Journal of Musculoskeletal Research
IS - 1-2
M1 - 1950001
ER -