Anterior pituitary involvement in Wegener's granulomatosis

K. M. Lohr, L. M. Ryan, R. J. Toohill, T. Anderson

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Wegener's granulomatosis rarely involves the pituitary, and is limited to the posterior gland. A young woman developed sinusitis, otitis media, asymptomatic pulmonary density, blindness, and anterior pituitary hormone deficiency over 7 years. Mucosal biopsies showed only chronic necrotizing inflammation without vasculitis. Since her clinical course suggested an atypical presentation of Wegener's granulomatosis, cyclophosphamide was finally added to corticosteroid therapy. All symptoms but monocular blindness and hypopituitarism remitted.

Original languageEnglish
Pages (from-to)855-857
Number of pages3
JournalJournal of Rheumatology
Volume15
Issue number5
StatePublished - 1988

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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