Antibiotic resistance of gram-negative enteric bacteria from pigs in three herds with different histories of antibiotic exposure

G. Gellin, B. E. Langlois, K. A. Dawson, D. K. Aaron

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48 Scopus citations

Abstract

The antibiotic resistance patterns of gram-negative fecal bacteria from pigs in three herds with different histories of antibiotic exposure were examined. In general, smaller proportions of antibiotic-resistant or multiply resistant fecal isolates (P < 0.05) were obtained from pigs in a herd not exposed to antimicrobial agents for 154 months than from pigs in a herd continuously exposed to antimicrobial agents at subtherapeutic doses or from pigs in a herd exposed only to therapeutic doses of antimicrobial agents. The proportions of antibiotic-resistant and multiply resistant strains were greater among isolates from pigs in the therapeutic herd than in the non-antibiotic-exposed herd (P < 0.05). The proportion of antibiotic-resistant isolates in the non-lactose-fermenting population was greater than that in the lactose-fermenting population, regardless of herd. The results suggest that any form of antimicrobial exposure will increase the prevalence of antimicrobial and multiple resistance of fecal bacteria.

Original languageEnglish
Pages (from-to)2287-2292
Number of pages6
JournalApplied and Environmental Microbiology
Volume55
Issue number9
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

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