Antigenic comparison of H3N8 equine influenza viruses belonging to Florida sublineage clade 1 between vaccine strains and North American strains isolated in 2021–2022

Manabu Nemoto, Stephanie E. Reedy, Takanori Yano, Kenya Suzuki, Shino Fukuda, Marie Garvey, Yoshinori Kambayashi, Hiroshi Bannai, Koji Tsujimura, Takashi Yamanaka, Ann Cullinane, Thomas M. Chambers

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Equine influenza virus strains of Florida sublineage clade 1 (Fc1) have been circulating in North America. In this study, virus neutralization assays were performed to evaluate antigenic differences between Fc1 vaccine strains and North American Fc1 strains isolated in 2021–2022, using equine antisera against A/equine/South Africa/4/2003 (a vaccine strain recommended by the World Organisation for Animal Health) and A/equine/Ibaraki/1/2007 (a Japanese vaccine strain). Antibody titers against four North American Fc1 strains isolated in 2021–2022 were comparable to those against the homologous vaccine strains. These results suggest that current Fc1 vaccine strains are effective against North American strains from 2021–2022.

Original languageEnglish
Article number94
JournalArchives of Virology
Volume168
Issue number3
DOIs
StatePublished - Mar 2023

Bibliographical note

Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.

Keywords

  • Equine influenza virus
  • Florida sublineage clade 1
  • Neutralization assay
  • Vaccine

ASJC Scopus subject areas

  • Virology

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