Antimicrobial Resistance and Recent Alternatives to Antibiotics for the Control of Bacterial Pathogens with an Emphasis on Foodborne Pathogens

Yosra A. Helmy; Khaled Taha-Abdelaziz; Hanan Abd El Halim Hawwas; Soumya Ghosh; Samar Sami AlKafaas; Mohamed M.M. Moawad; Essa M. Saied; Issmat I. Kassem; Asmaa M.M. Mawad

doi:10.3390/antibiotics12020274

Antimicrobial Resistance and Recent Alternatives to Antibiotics for the Control of Bacterial Pathogens with an Emphasis on Foodborne Pathogens

Yosra A. Helmy, Khaled Taha-Abdelaziz, Hanan Abd El Halim Hawwas, Soumya Ghosh, Samar Sami AlKafaas, Mohamed M.M. Moawad, Essa M. Saied, Issmat I. Kassem, Asmaa M.M. Mawad

Research output: Contribution to journal › Review article › peer-review

55 Scopus citations

Abstract

Antimicrobial resistance (AMR) is one of the most important global public health problems. The imprudent use of antibiotics in humans and animals has resulted in the emergence of antibiotic-resistant bacteria. The dissemination of these strains and their resistant determinants could endanger antibiotic efficacy. Therefore, there is an urgent need to identify and develop novel strategies to combat antibiotic resistance. This review provides insights into the evolution and the mechanisms of AMR. Additionally, it discusses alternative approaches that might be used to control AMR, including probiotics, prebiotics, antimicrobial peptides, small molecules, organic acids, essential oils, bacteriophage, fecal transplants, and nanoparticles.

Original language	English
Article number	274
Journal	Antibiotics
Volume	12
Issue number	2
DOIs	https://doi.org/10.3390/antibiotics12020274
State	Published - Feb 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

Keywords

antibiotics alternatives
antibodies
antimicrobial peptides
antimicrobial resistance
bacteriophage
essential oils
fecal transplant
nanoparticles
organic acids
prebiotics
probiotics
quorum sensing
small molecules
vaccines

ASJC Scopus subject areas

Microbiology
Biochemistry
Pharmacology, Toxicology and Pharmaceutics (all)
Microbiology (medical)
Infectious Diseases
Pharmacology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/antibiotics12020274

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Helmy, Y. A., Taha-Abdelaziz, K., Hawwas, H. A. E. H., Ghosh, S., AlKafaas, S. S., Moawad, M. M. M., Saied, E. M., Kassem, I. I., & Mawad, A. M. M. (2023). Antimicrobial Resistance and Recent Alternatives to Antibiotics for the Control of Bacterial Pathogens with an Emphasis on Foodborne Pathogens. Antibiotics, 12(2), Article 274. https://doi.org/10.3390/antibiotics12020274

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abstract = "Antimicrobial resistance (AMR) is one of the most important global public health problems. The imprudent use of antibiotics in humans and animals has resulted in the emergence of antibiotic-resistant bacteria. The dissemination of these strains and their resistant determinants could endanger antibiotic efficacy. Therefore, there is an urgent need to identify and develop novel strategies to combat antibiotic resistance. This review provides insights into the evolution and the mechanisms of AMR. Additionally, it discusses alternative approaches that might be used to control AMR, including probiotics, prebiotics, antimicrobial peptides, small molecules, organic acids, essential oils, bacteriophage, fecal transplants, and nanoparticles.",

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AU - Ghosh, Soumya

AU - AlKafaas, Samar Sami

AU - Moawad, Mohamed M.M.

AU - Saied, Essa M.

AU - Kassem, Issmat I.

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AB - Antimicrobial resistance (AMR) is one of the most important global public health problems. The imprudent use of antibiotics in humans and animals has resulted in the emergence of antibiotic-resistant bacteria. The dissemination of these strains and their resistant determinants could endanger antibiotic efficacy. Therefore, there is an urgent need to identify and develop novel strategies to combat antibiotic resistance. This review provides insights into the evolution and the mechanisms of AMR. Additionally, it discusses alternative approaches that might be used to control AMR, including probiotics, prebiotics, antimicrobial peptides, small molecules, organic acids, essential oils, bacteriophage, fecal transplants, and nanoparticles.

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KW - antimicrobial peptides

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KW - bacteriophage

KW - essential oils

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Antimicrobial Resistance and Recent Alternatives to Antibiotics for the Control of Bacterial Pathogens with an Emphasis on Foodborne Pathogens

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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