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Antimicrobial Resistance and Recent Alternatives to Antibiotics for the Control of Bacterial Pathogens with an Emphasis on Foodborne Pathogens

  • Yosra A. Helmy
  • , Khaled Taha-Abdelaziz
  • , Hanan Abd El Halim Hawwas
  • , Soumya Ghosh
  • , Samar Sami AlKafaas
  • , Mohamed M.M. Moawad
  • , Essa M. Saied
  • , Issmat I. Kassem
  • , Asmaa M.M. Mawad

Research output: Contribution to journalReview articlepeer-review

171 Scopus citations

Abstract

Antimicrobial resistance (AMR) is one of the most important global public health problems. The imprudent use of antibiotics in humans and animals has resulted in the emergence of antibiotic-resistant bacteria. The dissemination of these strains and their resistant determinants could endanger antibiotic efficacy. Therefore, there is an urgent need to identify and develop novel strategies to combat antibiotic resistance. This review provides insights into the evolution and the mechanisms of AMR. Additionally, it discusses alternative approaches that might be used to control AMR, including probiotics, prebiotics, antimicrobial peptides, small molecules, organic acids, essential oils, bacteriophage, fecal transplants, and nanoparticles.

Original languageEnglish
Article number274
JournalAntibiotics
Volume12
Issue number2
DOIs
StatePublished - Feb 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • antibiotics alternatives
  • antibodies
  • antimicrobial peptides
  • antimicrobial resistance
  • bacteriophage
  • essential oils
  • fecal transplant
  • nanoparticles
  • organic acids
  • prebiotics
  • probiotics
  • quorum sensing
  • small molecules
  • vaccines

ASJC Scopus subject areas

  • Microbiology
  • Biochemistry
  • Pharmacology, Toxicology and Pharmaceutics (all)
  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)

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