Aortic and Mitral Valve Replacement in Idiopathic Hypereosinophilic Syndrome

William G. Hendren, Ellis L. Jones, Mikel D. Smith

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


Idiopathic hypereosinophilic syndrome is a rare systemic manifestation of eosinophilia that may cause endocardial fibrosis. Endocardial fibrosis and overlying thrombus typically lead to a restrictive cardiomyopathy and heart failure. Occasionally mitral or tricuspid regurgitation (or both) occurs as a result of the fibrosis and thrombus formation. This report describes a patient with hypereosinophilic syndrome who was seen with an unusually localized form of cardiac involvement that resulted in predominantly aortic and mitral stenosis. This was treated with bivalvular replacement.

Original languageEnglish
Pages (from-to)570-571
Number of pages2
JournalAnnals of Thoracic Surgery
Issue number5
StatePublished - 1988

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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