Aortic Aneurysms and Dissections Series: Part II: Dynamic Signaling Responses in Aortic Aneurysms and Dissections

Ying H. Shen, Scott A. LeMaire, Nancy R. Webb, Lisa A. Cassis, Alan Daugherty, Hong S. Lu

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations

Abstract

Aortic structure and function are controlled by the coordinated actions of different aortic cells and the extracellular matrix. Several pathways have been identified that control the aortic wall in a cell-type-specific manner and play diverse roles in various phases of aortic injury, repair, and remodeling. This complexity of signaling in the aortic wall poses challenges to the development of therapeutic strategies for treating aortic aneurysms and dissections. Here, in part II of this Recent Highlights series on aortic aneurysms and dissections, we will summarize recent studies published in Arteriosclerosis, Thrombosis, and Vascular Biology that have contributed to our knowledge of the signaling pathway-related mechanisms of aortic aneurysms and dissections.

Original languageEnglish
Pages (from-to)E78-E86
JournalArteriosclerosis, Thrombosis, and Vascular Biology
Volume40
Issue number4
DOIs
StatePublished - Apr 1 2020

Bibliographical note

Publisher Copyright:
© 2020 American Heart Association, Inc.

Keywords

  • angiotensin II receptor
  • aorta
  • aortic aneurysms
  • signal transduction pathways
  • transforming growth factor

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint

Dive into the research topics of 'Aortic Aneurysms and Dissections Series: Part II: Dynamic Signaling Responses in Aortic Aneurysms and Dissections'. Together they form a unique fingerprint.

Cite this