Apomorphine induction of AP-1 DNA binding in the rat striatum after dopamine depletion

K. R. Pennypacker; W. Q. Zhang; H. Ye; J. S. Hong

doi:10.1016/0169-328X(92)90163-6

Apomorphine induction of AP-1 DNA binding in the rat striatum after dopamine depletion

K. R. Pennypacker, W. Q. Zhang, H. Ye, J. S. Hong

Research output: Contribution to journal › Article › peer-review

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Abstract

The expression of AP-1 transcription factors was assessed in the dopamine-depleted rat striatum over a 1 week period of repeated apomorphine injections. A single injection of apomorphine increased the expression of a 35 kDa Fos-related antigen and Jun proteins and their expression continued to increase until day 3 of repeated apomorphine treatment in dopamine-depleted striata. Apomorphine induces AP-1 transcription factors which may be involved in modulating gene expression in the striatum.

Original language	English
Pages (from-to)	151-155
Number of pages	5
Journal	Molecular Brain Research
Volume	15
Issue number	1-2
DOIs	https://doi.org/10.1016/0169-328X(92)90163-6
State	Published - Sep 1992

Keywords

6-Hydroxydopamine
AP-1 DNA binding
Jun protein, Fos-related antigen
Striatum
Transcription factor
c-Fos protein

ASJC Scopus subject areas

Molecular Biology
Cellular and Molecular Neuroscience

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10.1016/0169-328X(92)90163-6

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title = "Apomorphine induction of AP-1 DNA binding in the rat striatum after dopamine depletion",

abstract = "The expression of AP-1 transcription factors was assessed in the dopamine-depleted rat striatum over a 1 week period of repeated apomorphine injections. A single injection of apomorphine increased the expression of a 35 kDa Fos-related antigen and Jun proteins and their expression continued to increase until day 3 of repeated apomorphine treatment in dopamine-depleted striata. Apomorphine induces AP-1 transcription factors which may be involved in modulating gene expression in the striatum.",

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AU - Pennypacker, K. R.

AU - Zhang, W. Q.

AU - Ye, H.

AU - Hong, J. S.

PY - 1992/9

Y1 - 1992/9

N2 - The expression of AP-1 transcription factors was assessed in the dopamine-depleted rat striatum over a 1 week period of repeated apomorphine injections. A single injection of apomorphine increased the expression of a 35 kDa Fos-related antigen and Jun proteins and their expression continued to increase until day 3 of repeated apomorphine treatment in dopamine-depleted striata. Apomorphine induces AP-1 transcription factors which may be involved in modulating gene expression in the striatum.

AB - The expression of AP-1 transcription factors was assessed in the dopamine-depleted rat striatum over a 1 week period of repeated apomorphine injections. A single injection of apomorphine increased the expression of a 35 kDa Fos-related antigen and Jun proteins and their expression continued to increase until day 3 of repeated apomorphine treatment in dopamine-depleted striata. Apomorphine induces AP-1 transcription factors which may be involved in modulating gene expression in the striatum.

KW - 6-Hydroxydopamine

KW - AP-1 DNA binding

KW - Jun protein, Fos-related antigen

KW - Striatum

KW - Transcription factor

KW - c-Fos protein

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JO - Molecular Brain Research

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ER -

Apomorphine induction of AP-1 DNA binding in the rat striatum after dopamine depletion

Abstract

Keywords

ASJC Scopus subject areas

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