Abstract
Calcium is necessary for the optimal growth and cellular functions of most living organisms. For example, Ca is involved in the processes of muscle contraction, stimulus-secretion coupling, bone formation, blood clotting, cell proliferation and motility, and fertilization. Many regulatory actions of Ca are mediated through Ca-binding proteins. Calcium-modulated proteins are a subclass of Ca-binding proteins that are thought to be the major signal transducers of Ca acting as a cellular second messenger. Most Ca-modulated proteins are not enzymes but are effector proteins capable of transducing a Ca signal into a biological response by their ability to bind Ca reversibly and modulate the activity of other proteins in a Ca-dependent manner. This review focuses on a set of Ca-modulated proteins, the S100 proteins, and their possible roles in mediating Ca-dependent cellular events.
Original language | English |
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Pages (from-to) | 2028-2034 |
Number of pages | 7 |
Journal | Journal of Dairy Science |
Volume | 71 |
Issue number | 8 |
DOIs | |
State | Published - 1988 |
Bibliographical note
Copyright:Copyright 2017 Elsevier B.V., All rights reserved.
ASJC Scopus subject areas
- Food Science
- Animal Science and Zoology
- Genetics