TY - JOUR
T1 - Assessment of personal exposure to manganese in children living near a ferromanganese refinery
AU - Haynes, Erin N.
AU - Ryan, Pat
AU - Chen, Aimin
AU - Brown, David
AU - Roda, Sandy
AU - Kuhnell, Pierce
AU - Wittberg, Dawn
AU - Terrell, Matthew
AU - Reponen, Tiina
PY - 2012/7/15
Y1 - 2012/7/15
N2 - Airborne exposure to manganese (Mn) can result in neurologic effects. Stationary air sampling is the traditional technique to assess Mn exposure for communities, yet may not accurately reflect children's personal exposure. The goal of the study was to characterize personal exposure to Mn and PM 2.5 in a cohort of children ages 7-9years residing near a ferromanganese refinery.A subset of children living in non-smoking households ages 7-9 enrolled in the Marietta Community Actively Researching Exposure Study during March-June 2009 and 2010 were invited to participate. Blood and hair were collected and analyzed for Mn. Participants wore a PM 2.5 sampler (Personal Modular Impactor) for 48h. TWD was based on time spent at home and school and the distance of each from the refinery. Stationary outdoor air sampling was conducted 8km from the refinery using a Harvard-type PM 2.5 impactor. The relationship between personal Mn exposure and TWD was examined by multiple regression adjusting for stationary air Mn concentration, wind speed and direction, and precipitation.Complete personal air sampling data were collected on 38 children. TWD ranged from 4.7. km to 28.5. km with a mean distance of 11.1 (4.7. sd) km. Mn concentration in personal air samples ranged from 1.5. ng/m3 to 54.5. ng/m3 (geometric mean, 8.1. ng/m3). TWD was a significant predictor of natural log personal air Mn concentration (lnMn) with an associated decrease of 0.075. lnMn for each km TWD (p < 0.05, 95% CI - 0.13 to - 0.01). Personal Mn exposures were positively associated with stationary air Mn levels and inversely associated with wind speed.A child's location (home and school) relative to the refinery is a significant predictor of personal Mn exposure. Wind speed is also an important contributor to personal Mn exposure.
AB - Airborne exposure to manganese (Mn) can result in neurologic effects. Stationary air sampling is the traditional technique to assess Mn exposure for communities, yet may not accurately reflect children's personal exposure. The goal of the study was to characterize personal exposure to Mn and PM 2.5 in a cohort of children ages 7-9years residing near a ferromanganese refinery.A subset of children living in non-smoking households ages 7-9 enrolled in the Marietta Community Actively Researching Exposure Study during March-June 2009 and 2010 were invited to participate. Blood and hair were collected and analyzed for Mn. Participants wore a PM 2.5 sampler (Personal Modular Impactor) for 48h. TWD was based on time spent at home and school and the distance of each from the refinery. Stationary outdoor air sampling was conducted 8km from the refinery using a Harvard-type PM 2.5 impactor. The relationship between personal Mn exposure and TWD was examined by multiple regression adjusting for stationary air Mn concentration, wind speed and direction, and precipitation.Complete personal air sampling data were collected on 38 children. TWD ranged from 4.7. km to 28.5. km with a mean distance of 11.1 (4.7. sd) km. Mn concentration in personal air samples ranged from 1.5. ng/m3 to 54.5. ng/m3 (geometric mean, 8.1. ng/m3). TWD was a significant predictor of natural log personal air Mn concentration (lnMn) with an associated decrease of 0.075. lnMn for each km TWD (p < 0.05, 95% CI - 0.13 to - 0.01). Personal Mn exposures were positively associated with stationary air Mn levels and inversely associated with wind speed.A child's location (home and school) relative to the refinery is a significant predictor of personal Mn exposure. Wind speed is also an important contributor to personal Mn exposure.
KW - Air pollution
KW - Children
KW - Exposure
KW - Manganese
KW - Particulate matter
KW - Personal air sampling
UR - http://www.scopus.com/inward/record.url?scp=84861185479&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861185479&partnerID=8YFLogxK
U2 - 10.1016/j.scitotenv.2012.03.037
DO - 10.1016/j.scitotenv.2012.03.037
M3 - Article
C2 - 22551936
AN - SCOPUS:84861185479
SN - 0048-9697
VL - 427-428
SP - 19
EP - 25
JO - Science of the Total Environment
JF - Science of the Total Environment
ER -