Abstract
Background: Physical activity has been associated with longer chronic disease-free life expectancy, but specific cancer types have not been investigated. We examined whether leisure-time moderate- to-vigorous physical activity (LTPA) and television (TV) viewing were associated with life expectancy cancer-free. Methods: We included 14,508 participants without a cancer history from the Atherosclerosis Risk in Communities (ARIC) study. We used multistate survival models to separately examine associations of LTPA (no LTPA, <median, ≥median) and TV viewing (seldom/never, sometimes, often/very often) with life expectancy cancer-free at age 50 from invasive colorectal, lung, prostate, and postmenopausal breast cancer. Models were adjusted for age, gender, race, ARIC center, education, smoking, and alcohol intake. Results: Compared with no LTPA, participants who engaged in LTPA ≥median had a greater life expectancy cancer-free from colorectal [men-2.2 years (95% confidence interval (CI), 1.7-2.7), women-2.3 years (95% CI, 1.7-2.8)], lung [men-2.1 years (95% CI, 1.5-2.6), women-2.1 years (95% CI, 1.6-2.7)], prostate [1.5 years (95% CI, 0.8-2.2)], and postmenopausal breast cancer [2.4 years (95% CI, 1.4-3.3)]. Compared with watching TV often/very often, participants who seldom/never watched TV had a greater colorectal, lung, and postmenopausal breast cancer-free life expectancy of ∼1 year. Conclusions: Participating in LTPA was associated with longer life expectancy cancer-free from colorectal, lung, prostate, and postmenopausal breast cancer. Viewing less TV was associated with more years lived cancer-free from colorectal, lung, and postmenopausal breast cancer. Impact: Increasing physical activity and reducing TV viewing may extend the number of years lived cancer-free.
| Original language | English |
|---|---|
| Pages (from-to) | 2617-2625 |
| Number of pages | 9 |
| Journal | Cancer Epidemiology Biomarkers and Prevention |
| Volume | 29 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 2020 |
Bibliographical note
Publisher Copyright:© 2020 American Association for Cancer Research.
Funding
The authors thank the staff and participants of the ARIC study for their important contributions. They thank Dr. Chirayath M. Suchindran for his guidance on multistate models and multistate life expectancies. C.C. Cuthbertson was supported by a National Heart, Lung, and Blood Institute National Research Service Award (NRSA: T32-HL007055). The Atherosclerosis Risk in Communities study has been funded in whole or in part with federal funds from the National Heart, Lung, and Blood Institute, NIH, Department of Health and Human Services, under contract nos. HHSN268201700001I, HHSN268201700002I, HHSN268201700003I, HHSN268201700005I, and HHSN268201700004I. Studies on cancer in ARIC are also supported by the NCI (U01 CA164975). Cancer incidence data have been provided by the Maryland Cancer Registry, Center for Cancer Surveillance and Control, Maryland Department of Health. The authors acknowledge the State of Maryland, the Maryland Cigarette Restitution Fund, and the National Program of Cancer Registries (NPCR) of the Centers for Disease Control and Prevention (CDC) for the funds that helped support the availability of the cancer registry data.
| Funders | Funder number |
|---|---|
| Centers for Disease Control and Prevention | |
| Maryland Cigarette Restitution Fund | |
| Maryland Department of Health | |
| National Institutes of Health (NIH) | |
| National Heart, Lung, and Blood Institute National Research Service Award | |
| Maryland Cancer Registry | |
| National Childhood Cancer Registry – National Cancer Institute | P30CA016086, U01CA164975 |
| U.S. Department of Health and Human Services | HHSN268201700003I, HHSN268201700004I, HHSN268201700005I, HHSN268201700001I, HHSN268201700002I |
| Israel National Road Safety Authority | T32-HL007055 |
| National Heart, Lung, and Blood Institute (NHLBI) | T32HL007055 |
ASJC Scopus subject areas
- General Medicine
