Asystole during treatment with amiodarone in a patient with persistent atrial tachycardia

Chien Suu Kuo, C. Pratap Reddy, Mark V. Paciotti

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

During treatment with amiodarone, digoxin and nadolol, asystole occurred repeatedly in a patient with chronic persistent automatic atrial tachycardia. Asystole did not occur after discontinuation of drug therapy, and rechallenge with amiodarone alone produced marked overdrive suppression of all pacemakers resulting in asystole. Amiodarone serum level was within therapeutic range. The possible electrophysiologic mechanisms by which amiodarone might suppress both normal and abnormal pacemakers are discussed. The occurrence of asystole at therapeutic serum concentration of amiodarone suggests that this drug should be used with caution.

Original languageEnglish
Pages (from-to)105-109
Number of pages5
JournalJournal of Electrocardiology
Volume18
Issue number1
DOIs
StatePublished - 1985

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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