Attenuation estimations using envelope echo data: Analysis and simulations

Haifeng Tu, James Zagzebski, Quan Chen

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Previously we described a video signal analysis (VSA) method for measuring backscatter and attenuation from B-Mode image data. VSA computes depth-dependent ratios of the mean echo intensity from a sample to the mean echo intensity from a reference phantom imaged using identical scanner settings. The slope of a line-fit of this ratio (expressed in dB) versus depth is related to the attenuation of the sample. This paper investigates conditions for which the echo intensity ratio versus depth is independent of transducer pulsing characteristics and instrument settings, and depends only on the properties of the sample and the reference. A theoretical model is described for the echo signal power versus depth from a uniform medium containing scatterers. The model incorporates bandwidth, frequency and media attenuation. Results show that the sample-to-reference echo intensity ratio versus depth is a curve, the departure of which from a straight line is a function of the relative attenuation of the two media, the imaging system bandwidth and the initial frequency. The model also leads to a depth-dependent "effective frequency" determination in the VSA method. Model predictions are verified using RF signals computed by an acoustic pulse-echo simulation program.

Original languageEnglish
Pages (from-to)377-386
Number of pages10
JournalUltrasound in Medicine and Biology
Issue number3
StatePublished - Mar 2006

Bibliographical note

Funding Information:
This work is supported in part by NIH grants R21EB002722 and R01CA100373.


  • Attenuation
  • Simulations
  • Tissue characterization
  • Video signal analysis

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Biophysics
  • Acoustics and Ultrasonics


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