Abstract
Background: Patients' attitudes toward deprescribing are crucial to understand before developing interventions, but no such data exists in the medically underserved, health disparities population of rural Appalachian United States. Objective(s): Assess Appalachian women's openness to deprescribing medications and determine if polypharmacy influenced their attitudes toward deprescribing. Methods: Before and after a cognitive behavioral therapy intervention, middle-aged Appalachian women self-reported medication use and completed the revised Patients’ Attitudes Toward Deprescribing Questionnaire (rPATD). Responses were described, stratified by presence of polypharmacy. Results: 30 women completed the rPATD pre- and post-intervention (mean [SD] age 55.8 [6.6] years; 96.7% white). Those with polypharmacy (n = 16) had higher burden and involvement scores (median 2.8 vs 2.0, p = 0.01; 4.9 vs 4.6, p = 0.06), and lower appropriateness scores (3.4 vs 3.9, p = 0.04). Burden, concerns about stopping, and involvement factor scores were similar before and after the intervention (p = 0.08, 0.86, and 0.41 respectively). ≥90% of participants were satisfied with their current medications yet would be willing to stop one or more. Conclusions: Middle-aged women in rural Appalachian United States are open to deprescribing; polypharmacy is associated with lower belief in the appropriateness of medications. Larger studies are needed to inform future deprescribing interventions for this and other similarly disadvantaged populations.
Original language | English |
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Pages (from-to) | 1502-1507 |
Number of pages | 6 |
Journal | Research in Social and Administrative Pharmacy |
Volume | 16 |
Issue number | 10 |
DOIs | |
State | Published - Oct 2020 |
Bibliographical note
Funding Information:Funding Sources: This work was supported by the Building Interdisciplinary Research Careers in Women's Health Program under the National Institute on Drug Abuse [ K12-DA035150 ], the National Institute on Aging [ R01-AG054130 ], the University of Kentucky Center for Clinical and Translational Sciences [ UL1-TROO1998 ], and pilot funding from the Igniting Research Collaborations Grant (University of Kentucky College of Pharmacy) . ER is supported by a Dementia Research Development fellowship from National Health and Medical Research Council-Australian Research Council .
Funding Information:
ER reports a Dementia Research Development Fellowship from National Health and Medical Research Council-Australian Research Council.
Funding Information:
MM, CB, and DM report grants from the Building Interdisciplinary Research Careers in Women's Health Program under the National Institute on Drug Abuse during the conduct of the study.
Publisher Copyright:
© 2020
Keywords
- Deprescribing
- Health disparities
- Medication appropriateness
ASJC Scopus subject areas
- Pharmacy
- Pharmaceutical Science