Atypical MOG antibody disease presenting with typical multiple sclerosis lesions

Katelyn Dolbec, Joshua Chalkley, Padmaja Sudhakar

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Myelin oligodendrocyte glycoprotein (MOG) antibody disease is an autoimmune disease of the central nervous system associated with a serological antibody against MOG, a glycoprotein expressed on the outer membrane of myelin. It is solely found within the central nervous system in the brain, optic nerves and spinal cord. MOG antibody disease falls within the neuromyelitis optica spectrum disorders (NMOSD), however clinical characteristics appear distinct from aquaporin-4 antibody related disease and multiple sclerosis. It has predilection for causing recurrent optic neuritis and transverse myelitis. Accurate diagnosis is important to determine long term prognosis and suitable treatment. We describe the case of a 42 year old woman previously labelled as MS who demonstrated a variable presentation of MOG antibody disease.

Original languageEnglish
Article number102342
JournalMultiple Sclerosis and Related Disorders
StatePublished - Sep 2020

Bibliographical note

Publisher Copyright:
© 2020 Elsevier B.V.

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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