Autoradiographic localization of binding sites for 2-[125I]iodomelatonin in the pars tuberalis of the western spotted skunk (Spilogale putorius latifrons)

Marilyn J. Duncan; Rodney A. Mead

doi:10.1016/0006-8993(92)90382-J

Autoradiographic localization of binding sites for 2-[¹²⁵I]iodomelatonin in the pars tuberalis of the western spotted skunk (Spilogale putorius latifrons)

Marilyn J. Duncan, Rodney A. Mead

Neuroscience

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Pineal melatonin secretion mediates photoperiodic regulation of implantation of blastocysts in the female western spotted skunk. Autoradiography studies demonstrated that high affinity 2-[¹²⁵I]iodomelatonin binding sites are present in the pars tuberalis but not in any other hypophyseal region or in the hypothalamus or thalamus of this pieces. This restricted localization of 2-[¹²⁵I]iodemelatonin binding, which was characteristic of spotted skunks sacrificed at various times during their annual reproductive cycles, suggests that the pars tuberalis mediates photoperiodic responses in this species.

Original language	English
Pages (from-to)	152-155
Number of pages	4
Journal	Brain Research
Volume	569
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(92)90382-J
State	Published - Jan 8 1992

Bibliographical note

Funding Information:
The authors appreciate the technical assistance of Joseph L. Johnson and Sandra Neirinckx. These studies were supported by USPHS Grants DK-42056 (to M.J.D.) and HD-06556 (to R.A.M.) and an award from the University of Missouri Medical School Research Council (to M.J.D.)

Funding

The authors appreciate the technical assistance of Joseph L. Johnson and Sandra Neirinckx. These studies were supported by USPHS Grants DK-42056 (to M.J.D.) and HD-06556 (to R.A.M.) and an award from the University of Missouri Medical School Research Council (to M.J.D.)

Funders	Funder number
University of Missouri Medical School Research Council
U.S. Public Health Service	HD-06556, DK-42056
Eunice Kennedy Shriver National Institute of Child Health and Human Development	R01HD006556

Keywords

Adenohypophysis
Autoradiography
Implantation
Melatonin
Photoperiod
Pineal

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

Access to Document

10.1016/0006-8993(92)90382-J

Cite this

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title = "Autoradiographic localization of binding sites for 2-[125I]iodomelatonin in the pars tuberalis of the western spotted skunk (Spilogale putorius latifrons)",

abstract = "Pineal melatonin secretion mediates photoperiodic regulation of implantation of blastocysts in the female western spotted skunk. Autoradiography studies demonstrated that high affinity 2-[125I]iodomelatonin binding sites are present in the pars tuberalis but not in any other hypophyseal region or in the hypothalamus or thalamus of this pieces. This restricted localization of 2-[125I]iodemelatonin binding, which was characteristic of spotted skunks sacrificed at various times during their annual reproductive cycles, suggests that the pars tuberalis mediates photoperiodic responses in this species.",

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author = "Duncan, \{Marilyn J.\} and Mead, \{Rodney A.\}",

note = "Funding Information: The authors appreciate the technical assistance of Joseph L. Johnson and Sandra Neirinckx. These studies were supported by USPHS Grants DK-42056 (to M.J.D.) and HD-06556 (to R.A.M.) and an award from the University of Missouri Medical School Research Council (to M.J.D.)",

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AU - Mead, Rodney A.

N1 - Funding Information: The authors appreciate the technical assistance of Joseph L. Johnson and Sandra Neirinckx. These studies were supported by USPHS Grants DK-42056 (to M.J.D.) and HD-06556 (to R.A.M.) and an award from the University of Missouri Medical School Research Council (to M.J.D.)

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N2 - Pineal melatonin secretion mediates photoperiodic regulation of implantation of blastocysts in the female western spotted skunk. Autoradiography studies demonstrated that high affinity 2-[125I]iodomelatonin binding sites are present in the pars tuberalis but not in any other hypophyseal region or in the hypothalamus or thalamus of this pieces. This restricted localization of 2-[125I]iodemelatonin binding, which was characteristic of spotted skunks sacrificed at various times during their annual reproductive cycles, suggests that the pars tuberalis mediates photoperiodic responses in this species.

AB - Pineal melatonin secretion mediates photoperiodic regulation of implantation of blastocysts in the female western spotted skunk. Autoradiography studies demonstrated that high affinity 2-[125I]iodomelatonin binding sites are present in the pars tuberalis but not in any other hypophyseal region or in the hypothalamus or thalamus of this pieces. This restricted localization of 2-[125I]iodemelatonin binding, which was characteristic of spotted skunks sacrificed at various times during their annual reproductive cycles, suggests that the pars tuberalis mediates photoperiodic responses in this species.

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