Autoradiographic localization of binding sites for 2-[125I]iodomelatonin in the pars tuberalis of the western spotted skunk (Spilogale putorius latifrons)

Marilyn J. Duncan, Rodney A. Mead

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Pineal melatonin secretion mediates photoperiodic regulation of implantation of blastocysts in the female western spotted skunk. Autoradiography studies demonstrated that high affinity 2-[125I]iodomelatonin binding sites are present in the pars tuberalis but not in any other hypophyseal region or in the hypothalamus or thalamus of this pieces. This restricted localization of 2-[125I]iodemelatonin binding, which was characteristic of spotted skunks sacrificed at various times during their annual reproductive cycles, suggests that the pars tuberalis mediates photoperiodic responses in this species.

Original languageEnglish
Pages (from-to)152-155
Number of pages4
JournalBrain Research
Volume569
Issue number1
DOIs
StatePublished - Jan 8 1992

Bibliographical note

Funding Information:
The authors appreciate the technical assistance of Joseph L. Johnson and Sandra Neirinckx. These studies were supported by USPHS Grants DK-42056 (to M.J.D.) and HD-06556 (to R.A.M.) and an award from the University of Missouri Medical School Research Council (to M.J.D.)

Keywords

  • Adenohypophysis
  • Autoradiography
  • Implantation
  • Melatonin
  • Photoperiod
  • Pineal

ASJC Scopus subject areas

  • General Neuroscience
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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