Barriers to Buprenorphine Dispensing by Medicaid-Participating Community Retail Pharmacies

Patricia R Freeman, Lindsey R Hammerslag, Katherine A Ahrens, Michael Sharbaugh, Adam J Gordon, Anna E Austin, Julie M Donohue, Lindsay D Allen, Andrew J Barnes, Jeffery C Talbert

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

IMPORTANCE: Controlled substances have regulatory requirements under the US Federal Controlled Substance Act that must be met before pharmacies can stock and dispense them. However, emerging evidence suggests there are pharmacy-level barriers in access to buprenorphine for treatment for opioid use disorder even among pharmacies that dispense other opioids.

OBJECTIVE: To estimate the proportion of Medicaid-participating community retail pharmacies that dispense buprenorphine, out of Medicaid-participating community retail pharmacies that dispense other opioids and assess if the proportion dispensing buprenorphine varies by Medicaid patient volume or rural-urban location.

DESIGN, SETTING, AND PARTICIPANTS: This serial cross-sectional study included Medicaid pharmacy claims (2016-2019) data from 6 states (Kentucky, Maine, North Carolina, Pennsylvania, Virginia, West Virginia) participating in the Medicaid Outcomes Distributed Research Network (MODRN). Community retail pharmacies serving Medicaid-enrolled patients were included, mail-order pharmacies were excluded. Analyses were conducted from September 2022 to August 2023.

MAIN OUTCOMES AND MEASURES: The proportion of pharmacies dispensing buprenorphine approved for opioid use disorder among pharmacies dispensing an opioid analgesic or buprenorphine prescription to at least 1 Medicaid enrollee in each state. Pharmacies were categorized by median Medicaid patient volume (by state and year) and rurality (urban vs rural location according to zip code).

RESULTS: In 2016, 72.0% (95% CI, 70.9%-73.0%) of the 7038 pharmacies that dispensed opioids also dispensed buprenorphine to Medicaid enrollees, increasing to 80.4% (95% CI, 79.5%-81.3%) of 7437 pharmacies in 2019. States varied in the percent of pharmacies dispensing buprenorphine in Medicaid (range, 73.8%-96.4%), with significant differences between several states found in 2019 (χ2 P < .05), when states were most similar in the percent of pharmacies dispensing buprenorphine. A lower percent of pharmacies with Medicaid patient volume below the median dispensed buprenorphine (69.1% vs 91.7% in 2019), compared with pharmacies with above-median patient volume (χ2 P < .001).

CONCLUSIONS AND RELEVANCE: In this serial cross-sectional study of Medicaid-participating pharmacies, buprenorphine was not accessible in up to 20% of community retail pharmacies, presenting pharmacy-level barriers to patients with Medicaid seeking buprenorphine treatment. That some pharmacies dispensed opioid analgesics but not buprenorphine suggests that factors other than compliance with the Controlled Substance Act influence pharmacy dispensing decisions.

Original languageEnglish
Pages (from-to)e241077
JournalJAMA Health Forum
Volume5
Issue number5
DOIs
StatePublished - May 3 2024

Keywords

  • Humans
  • Medicaid/statistics & numerical data
  • Buprenorphine/therapeutic use
  • United States
  • Cross-Sectional Studies
  • Health Services Accessibility/statistics & numerical data
  • Opioid-Related Disorders/drug therapy
  • Pharmacies/statistics & numerical data
  • Community Pharmacy Services/statistics & numerical data
  • Opiate Substitution Treatment/statistics & numerical data
  • Narcotic Antagonists/therapeutic use

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