TY - JOUR
T1 - Be sure to read the fine print
T2 - The agency for healthcare research and quality comparative effectiveness report on antiepileptic drugs
AU - Welty, Timothy E.
AU - Faught, Edward
AU - Schmidt, Dieter
AU - McAuley, James W.
AU - Ryan, Melody
PY - 2012/5
Y1 - 2012/5
N2 - For many questions related to the pharmacotherapy of epilepsy, there are few or no published data. This lack of data presents dilemmas to practitioners who must make informed, rational decisions about therapy on a daily basis and to policymakers dealing with drug formulary management and reimbursement. Reliance on randomized, clinical trial data is inefficient because of the extensive time and expense involved in conducting a study and the inability to answer every question encountered in practice. In addition, results from randomized, clinical studies are not fully applicable in the clinical setting because of short trial duration and the frequent use of surrogate controls that are rarely seen in routine practice.
AB - For many questions related to the pharmacotherapy of epilepsy, there are few or no published data. This lack of data presents dilemmas to practitioners who must make informed, rational decisions about therapy on a daily basis and to policymakers dealing with drug formulary management and reimbursement. Reliance on randomized, clinical trial data is inefficient because of the extensive time and expense involved in conducting a study and the inability to answer every question encountered in practice. In addition, results from randomized, clinical studies are not fully applicable in the clinical setting because of short trial duration and the frequent use of surrogate controls that are rarely seen in routine practice.
UR - http://www.scopus.com/inward/record.url?scp=84870276884&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84870276884&partnerID=8YFLogxK
U2 - 10.5698/1535-7511-12.3.84
DO - 10.5698/1535-7511-12.3.84
M3 - Comment/debate
C2 - 22690134
AN - SCOPUS:84870276884
SN - 1535-7597
VL - 12
SP - 84
EP - 86
JO - Epilepsy Currents
JF - Epilepsy Currents
IS - 3
ER -