Behavioral, neurophysiological, and descriptive changes after occupation-based intervention

Camille Skubik-Peplaski, Cheryl Carrico, Laurel Nichols, Kenneth Chelette, Lumy Sawaki

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


OBJECTIVE. We evaluated the effects of occupation-based intervention on poststroke upper-extremity (UE) motor recovery, neuroplastic change, and occupational performance in 1 research participant. METHOD. A 55-yr-old man with chronic stroke and moderately impaired UE motor function participated in 15 sessions of occupation-based intervention in a hospital setting designed to simulate a home environment. We tested behavioral motor function (Fugl-Meyer Assessment, Stroke Impact Scale, Canadian Occupational Performance Measure) and neuroplasticity (transcranial magnetic stimulation [TMS]) at baseline and at completion of intervention. We collected descriptive data on occupational participation throughout the study. RESULTS. All behavioral outcomes indicated clinically relevant improvement. TMS revealed bihemispheric corticomotor reorganization. Descriptive data revealed enhanced occupational performance. CONCLUSION. Occupation-based intervention delivered in a hospital-based, homelike environment can lead to poststroke neuroplastic change, increased functional use of the affected UE, and improved occupational performance.

Original languageEnglish
Pages (from-to)e107-e113
JournalAmerican Journal of Occupational Therapy
Issue number6
StatePublished - Nov 2012


  • Activities of daily living
  • Motor skills
  • Neuronal plasticity
  • Recovery of function
  • Stroke

ASJC Scopus subject areas

  • Occupational Therapy


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