Bilateral macrostomia in one of monozygotic twins

James K. Hartsfield; David Bixler

doi:10.1016/0030-4220(84)90288-3

Bilateral macrostomia in one of monozygotic twins

James K. Hartsfield, David Bixler

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

This report concerns a pair of monozygotic twins discordant for bilateral symmetrical macrostomia. Laterally placed, symmetrical notches in the vermilion borders of both upper and lower lips were apparent in the affected twin. Since the oral cavity walls develop by a differential growth and merging mechanism, this result suggests a mechanism of tissue breakdown as the cause of macrostomia. Furthermore, discordance in these monozygotic twins minimizes the importance of heredity in this malformation.

Original language	English
Pages (from-to)	648-651
Number of pages	4
Journal	Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Volume	57
Issue number	6
DOIs	https://doi.org/10.1016/0030-4220(84)90288-3
State	Published - Jun 1984

Bibliographical note

Funding Information:
Supported in part by the Oral Facial Genetics Training Grant DE 7043 from the National Institutes of Health. *At present Research Fellow in Orthodontics at Harvard School of Dental Medicine, Boston, Mass.

ASJC Scopus subject areas

Pathology and Forensic Medicine
General Dentistry

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title = "Bilateral macrostomia in one of monozygotic twins",

abstract = "This report concerns a pair of monozygotic twins discordant for bilateral symmetrical macrostomia. Laterally placed, symmetrical notches in the vermilion borders of both upper and lower lips were apparent in the affected twin. Since the oral cavity walls develop by a differential growth and merging mechanism, this result suggests a mechanism of tissue breakdown as the cause of macrostomia. Furthermore, discordance in these monozygotic twins minimizes the importance of heredity in this malformation.",

author = "Hartsfield, {James K.} and David Bixler",

note = "Funding Information: Supported in part by the Oral Facial Genetics Training Grant DE 7043 from the National Institutes of Health. *At present Research Fellow in Orthodontics at Harvard School of Dental Medicine, Boston, Mass.",

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AU - Bixler, David

N1 - Funding Information: Supported in part by the Oral Facial Genetics Training Grant DE 7043 from the National Institutes of Health. *At present Research Fellow in Orthodontics at Harvard School of Dental Medicine, Boston, Mass.

PY - 1984/6

Y1 - 1984/6

N2 - This report concerns a pair of monozygotic twins discordant for bilateral symmetrical macrostomia. Laterally placed, symmetrical notches in the vermilion borders of both upper and lower lips were apparent in the affected twin. Since the oral cavity walls develop by a differential growth and merging mechanism, this result suggests a mechanism of tissue breakdown as the cause of macrostomia. Furthermore, discordance in these monozygotic twins minimizes the importance of heredity in this malformation.

AB - This report concerns a pair of monozygotic twins discordant for bilateral symmetrical macrostomia. Laterally placed, symmetrical notches in the vermilion borders of both upper and lower lips were apparent in the affected twin. Since the oral cavity walls develop by a differential growth and merging mechanism, this result suggests a mechanism of tissue breakdown as the cause of macrostomia. Furthermore, discordance in these monozygotic twins minimizes the importance of heredity in this malformation.

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JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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ER -

Bilateral macrostomia in one of monozygotic twins

Abstract

Bibliographical note

ASJC Scopus subject areas

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