Abstract
Bioassay-guided fractionation and chromatographic purification of the crude extract of ruminal bacterium Enterobacter amnigenus ZIH (isolated from cattle) produce one new microbial product:butyl-α-D-glucopyranoside together with eleven known compounds including (S)-brevinic acid, 3-(hydroxyacetyl)-indole, Nß-acetyltryptamine, tyrosol, phenol, tryptophol, indole-3-lactic acid, uracil, adenine and two diketopiperazines cyclo-(Phe, Pro) and cyclo-(Leu, Pro). The complete NMR assignments of butyl-α-D-glucopyranoside was done-using different spectroscopic (1H,13C,1H-1H COSY, HMQC, and HMBC) and spectrometric methods (ESI-MS, HRESI-MS). Compounds 1a and 2 reported for the first time from a natural source. The bacterial extract exhibited high cytotoxicity against brine shrimp and moderate antimicrobial activity against a diverse set of pathogenic bacteria strains.
| Original language | English |
|---|---|
| Pages (from-to) | 222-228 |
| Number of pages | 7 |
| Journal | Indian Journal of Natural Products and Resources |
| Volume | 9 |
| Issue number | 3 |
| State | Published - Sep 2018 |
Bibliographical note
Publisher Copyright:© 2019, National Institute of Science Communication and Information Resources (NISCAIR). All rights reserved.
Keywords
- Biological activities
- Brevinic acid
- Butyl-glucoside
- Enterobacter amnigenus ZIH
- Ruminal bacteria
ASJC Scopus subject areas
- Food Science
- Agronomy and Crop Science
- Plant Science