Biological Functions and Clinical Applications of Anti-Müllerian Hormone in Stallions and Mares

Anthony N.J. Claes; Barry A. Ball

doi:10.1016/j.cveq.2016.07.004

Biological Functions and Clinical Applications of Anti-Müllerian Hormone in Stallions and Mares

Anthony N.J. Claes, Barry A. Ball

Veterinary Science

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

Abstract

Anti-Müllerian hormone (AMH) plays a major role in sexual differentiation, Leydig cell differentiation, and folliculogenesis. In addition, AMH has clinical value in equine practice. In stallions, AMH can serve as an endocrine marker for equine cryptorchidism and as an immunohistochemical marker for Sertoli cell tumors. Considering that AMH is also an ovarian specific product, intact mares can be differentiated from ovariectomized mares. Peripheral AMH concentrations reflect the follicular population in mares, and therefore, are useful in the assessment of ovarian reserve and reproductive life-span of aged mares. Last, AMH is particularly suitable as a diagnostic marker for equine granulosa cell tumors.

Original language	English
Pages (from-to)	451-464
Number of pages	14
Journal	Veterinary Clinics of North America - Equine Practice
Volume	32
Issue number	3
DOIs	https://doi.org/10.1016/j.cveq.2016.07.004
State	Published - Dec 1 2016

Bibliographical note

Publisher Copyright:
© 2016 Elsevier Inc.

Keywords

Anti-Müllerian hormone
Cryptorchidism
Equine
Equine granulosa cell tumor
Mare
Ovarian reserve
Sertoli cell tumor
Stallion

ASJC Scopus subject areas

Equine

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10.1016/j.cveq.2016.07.004

Cite this

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title = "Biological Functions and Clinical Applications of Anti-M{\"u}llerian Hormone in Stallions and Mares",

abstract = "Anti-M{\"u}llerian hormone (AMH) plays a major role in sexual differentiation, Leydig cell differentiation, and folliculogenesis. In addition, AMH has clinical value in equine practice. In stallions, AMH can serve as an endocrine marker for equine cryptorchidism and as an immunohistochemical marker for Sertoli cell tumors. Considering that AMH is also an ovarian specific product, intact mares can be differentiated from ovariectomized mares. Peripheral AMH concentrations reflect the follicular population in mares, and therefore, are useful in the assessment of ovarian reserve and reproductive life-span of aged mares. Last, AMH is particularly suitable as a diagnostic marker for equine granulosa cell tumors.",

keywords = "Anti-M{\"u}llerian hormone, Cryptorchidism, Equine, Equine granulosa cell tumor, Mare, Ovarian reserve, Sertoli cell tumor, Stallion",

author = "Claes, {Anthony N.J.} and Ball, {Barry A.}",

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doi = "10.1016/j.cveq.2016.07.004",

language = "English",

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AU - Claes, Anthony N.J.

AU - Ball, Barry A.

PY - 2016/12/1

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N2 - Anti-Müllerian hormone (AMH) plays a major role in sexual differentiation, Leydig cell differentiation, and folliculogenesis. In addition, AMH has clinical value in equine practice. In stallions, AMH can serve as an endocrine marker for equine cryptorchidism and as an immunohistochemical marker for Sertoli cell tumors. Considering that AMH is also an ovarian specific product, intact mares can be differentiated from ovariectomized mares. Peripheral AMH concentrations reflect the follicular population in mares, and therefore, are useful in the assessment of ovarian reserve and reproductive life-span of aged mares. Last, AMH is particularly suitable as a diagnostic marker for equine granulosa cell tumors.

AB - Anti-Müllerian hormone (AMH) plays a major role in sexual differentiation, Leydig cell differentiation, and folliculogenesis. In addition, AMH has clinical value in equine practice. In stallions, AMH can serve as an endocrine marker for equine cryptorchidism and as an immunohistochemical marker for Sertoli cell tumors. Considering that AMH is also an ovarian specific product, intact mares can be differentiated from ovariectomized mares. Peripheral AMH concentrations reflect the follicular population in mares, and therefore, are useful in the assessment of ovarian reserve and reproductive life-span of aged mares. Last, AMH is particularly suitable as a diagnostic marker for equine granulosa cell tumors.

KW - Anti-Müllerian hormone

KW - Cryptorchidism

KW - Equine

KW - Equine granulosa cell tumor

KW - Mare

KW - Ovarian reserve

KW - Sertoli cell tumor

KW - Stallion

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JO - Veterinary Clinics of North America - Equine Practice

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Biological Functions and Clinical Applications of Anti-Müllerian Hormone in Stallions and Mares

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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