Biosynthetic Investigations on Pyridazomycin

Heike Bockholt; John M. Beale; Jürgen Rohr

doi:10.1002/anie.199416481

Biosynthetic Investigations on Pyridazomycin

Heike Bockholt, John M. Beale, Jürgen Rohr

Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

An unexpected amino acid metabolism is used by a subspecies of the soil bacterium Streptomyces violaceoniger to produce the antifungal antibiotic pyridazomycin 1‐C1. Feeding studies with isotopically labeled precursors indicate that 1 is constructed from ornithine, glycine, and probably oxaloacetate. (Figure Presented.)

Original language	English
Pages (from-to)	1648-1651
Number of pages	4
Journal	Angewandte Chemie International Edition in English
Volume	33
Issue number	15-16
DOIs	https://doi.org/10.1002/anie.199416481
State	Published - Sep 2 1994

ASJC Scopus subject areas

Catalysis
General Chemistry

Access to Document

10.1002/anie.199416481

Cite this

@article{6015d2b3f6ff42c09eb28ec633fa7465,

title = "Biosynthetic Investigations on Pyridazomycin",

abstract = "An unexpected amino acid metabolism is used by a subspecies of the soil bacterium Streptomyces violaceoniger to produce the antifungal antibiotic pyridazomycin 1‐C1. Feeding studies with isotopically labeled precursors indicate that 1 is constructed from ornithine, glycine, and probably oxaloacetate. (Figure Presented.)",

author = "Heike Bockholt and Beale, {John M.} and J{\"u}rgen Rohr",

year = "1994",

month = sep,

day = "2",

doi = "10.1002/anie.199416481",

language = "English",

volume = "33",

pages = "1648--1651",

number = "15-16",

}

TY - JOUR

T1 - Biosynthetic Investigations on Pyridazomycin

AU - Bockholt, Heike

AU - Beale, John M.

AU - Rohr, Jürgen

PY - 1994/9/2

Y1 - 1994/9/2

N2 - An unexpected amino acid metabolism is used by a subspecies of the soil bacterium Streptomyces violaceoniger to produce the antifungal antibiotic pyridazomycin 1‐C1. Feeding studies with isotopically labeled precursors indicate that 1 is constructed from ornithine, glycine, and probably oxaloacetate. (Figure Presented.)

AB - An unexpected amino acid metabolism is used by a subspecies of the soil bacterium Streptomyces violaceoniger to produce the antifungal antibiotic pyridazomycin 1‐C1. Feeding studies with isotopically labeled precursors indicate that 1 is constructed from ornithine, glycine, and probably oxaloacetate. (Figure Presented.)

UR - http://www.scopus.com/inward/record.url?scp=0028056144&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028056144&partnerID=8YFLogxK

U2 - 10.1002/anie.199416481

DO - 10.1002/anie.199416481

M3 - Article

AN - SCOPUS:0028056144

SN - 0570-0833

VL - 33

SP - 1648

EP - 1651

JO - Angewandte Chemie International Edition in English

JF - Angewandte Chemie International Edition in English

IS - 15-16

ER -

Biosynthetic Investigations on Pyridazomycin

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this