Blood plasma concentrations of insulin-like growth factor-I (IGF-I) in resting Standardbred Horses

Zahra J. Champion, B. H. Breier, W. E. Ewen, T. T. Tobin, P. J. Casey

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

A survey of standardbred horses was conducted to build up a normal population profile for insulin like growth factor-I (IGF-I) concentrations in racing standardbreds and to ascertain how age, sex and geographic location affect IGF-I. Blood samples were drawn by jugular venepuncture from 202 racing standardbred horses aged one to eight years located in five different geographic regions of New Zealand. IGF-I concentrations were determined by insulin like growth factor-I binding protein (IGFBP)-blocked radioimmunoassay validated for the horse. As described in other species, age played a significant (P<0.05) role in IGF-I concentrations with the highest concentrations occurring in the younger horses. There was a significant (P<0.05) sex effect, intact males having significantly higher IGF-I concentrations compared of mares and/or geldings. Geographic location had a significant (P <0.05) influence on IGF-I. A significant (P<0.05) trainer effect also was noted both within and between geographic locations. We concluded that IGF-I concentrations in racing standardbred horses are affected by age, sex, trainer and geographic location.

Original languageEnglish
Pages (from-to)45-50
Number of pages6
JournalVeterinary Journal
Volume163
Issue number1
DOIs
StatePublished - Jan 2002

Bibliographical note

Funding Information:
This work was funded by the Research Centre in Reproductive Medicine, Faculty of Medicine and Health Science, The University of Auckland.

Funding

This work was funded by the Research Centre in Reproductive Medicine, Faculty of Medicine and Health Science, The University of Auckland.

FundersFunder number
University of Auckland

    Keywords

    • Insulin-like growth factor-I
    • Population and horse
    • Standardbred horses

    ASJC Scopus subject areas

    • Animal Science and Zoology
    • General Veterinary

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