Blood plasma concentrations of insulin-like growth factor-I (IGF-I) in resting Standardbred Horses

Zahra J. Champion, B. H. Breier, W. E. Ewen, T. T. Tobin, P. J. Casey

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

A survey of standardbred horses was conducted to build up a normal population profile for insulin like growth factor-I (IGF-I) concentrations in racing standardbreds and to ascertain how age, sex and geographic location affect IGF-I. Blood samples were drawn by jugular venepuncture from 202 racing standardbred horses aged one to eight years located in five different geographic regions of New Zealand. IGF-I concentrations were determined by insulin like growth factor-I binding protein (IGFBP)-blocked radioimmunoassay validated for the horse. As described in other species, age played a significant (P<0.05) role in IGF-I concentrations with the highest concentrations occurring in the younger horses. There was a significant (P<0.05) sex effect, intact males having significantly higher IGF-I concentrations compared of mares and/or geldings. Geographic location had a significant (P <0.05) influence on IGF-I. A significant (P<0.05) trainer effect also was noted both within and between geographic locations. We concluded that IGF-I concentrations in racing standardbred horses are affected by age, sex, trainer and geographic location.

Original languageEnglish
Pages (from-to)45-50
Number of pages6
JournalVeterinary Journal
Volume163
Issue number1
DOIs
StatePublished - Jan 2002

Bibliographical note

Funding Information:
This work was funded by the Research Centre in Reproductive Medicine, Faculty of Medicine and Health Science, The University of Auckland.

Keywords

  • Insulin-like growth factor-I
  • Population and horse
  • Standardbred horses

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Veterinary (all)

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