BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability

Brian P. Delisle; Ezekiel Rozmus; Abhilash Prabhat; Spencer B. Procopio; Xiping Zhang; Emilia Entcheva; Karyn A. Esser; Elizabeth A. Schroder

doi:10.1016/j.hrthm.2025.10.007

BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability

Brian P. Delisle, Ezekiel Rozmus, Abhilash Prabhat, Spencer B. Procopio, Xiping Zhang, Emilia Entcheva, Karyn A. Esser, Elizabeth A. Schroder

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Heart Rhythm
DOIs	https://doi.org/10.1016/j.hrthm.2025.10.007
State	Accepted/In press - 2026

Funding

This work was supported by National Heart, Lung, and Blood Institute grants R01HL153042 , R01HL141343 , and R01HL172813 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Funders	Funder number
National Heart, Lung, and Blood Institute (NHLBI)	R01HL141343, R01HL153042, R01HL172813

Keywords

Arrhythmia
Autonomic
Circadian clock
Heart
Ion channels
Sex

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1016/j.hrthm.2025.10.007

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@article{58f0a1691457448d9930469cae884e18,

title = "BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability",

keywords = "Arrhythmia, Autonomic, Circadian clock, Heart, Ion channels, Sex",

author = "Delisle, \{Brian P.\} and Ezekiel Rozmus and Abhilash Prabhat and Procopio, \{Spencer B.\} and Xiping Zhang and Emilia Entcheva and Esser, \{Karyn A.\} and Schroder, \{Elizabeth A.\}",

year = "2026",

doi = "10.1016/j.hrthm.2025.10.007",

language = "English",

}

TY - JOUR

T1 - BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability

AU - Delisle, Brian P.

AU - Rozmus, Ezekiel

AU - Prabhat, Abhilash

AU - Procopio, Spencer B.

AU - Zhang, Xiping

AU - Entcheva, Emilia

AU - Esser, Karyn A.

AU - Schroder, Elizabeth A.

PY - 2026

Y1 - 2026

KW - Arrhythmia

KW - Autonomic

KW - Circadian clock

KW - Heart

KW - Ion channels

KW - Sex

UR - https://www.scopus.com/pages/publications/105026727099

UR - https://www.scopus.com/inward/citedby.url?scp=105026727099&partnerID=8YFLogxK

U2 - 10.1016/j.hrthm.2025.10.007

DO - 10.1016/j.hrthm.2025.10.007

M3 - Article

C2 - 41067479

AN - SCOPUS:105026727099

SN - 1547-5271

JO - Heart Rhythm

JF - Heart Rhythm

ER -

BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability

Funding

Keywords

ASJC Scopus subject areas

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