Boron dipyrromethene (BODIPY)-based photosensitizers for photodynamic therapy

Samuel G. Awuah, Youngjae You

Research output: Contribution to journalReview articlepeer-review

479 Scopus citations

Abstract

Photodynamic therapy (PDT) has shown promise as an effective treatment modality for cancers and other localized diseases, such as age-related macular degeneration and actinic keratosis. PDT relies on light, photosensitizer and oxygen as elements in its mechanism of action. BODIPY photosensitizers that have been under extensive study over the past decade have been demonstrated as a new class of photosensitizers. In this review, we attempt to summarize the decade-long study of BODIPY-based photosensitizers. We provide an overview of the superior photophysical properties possessed by BODIPY-based agents and the various synthetic strategies employed that have led to improved and selective and/or targeted photosensitizers.

Original languageEnglish
Pages (from-to)11169-11183
Number of pages15
JournalRSC Advances
Volume2
Issue number30
DOIs
StatePublished - Nov 28 2012

ASJC Scopus subject areas

  • Chemistry (all)
  • Chemical Engineering (all)

Fingerprint

Dive into the research topics of 'Boron dipyrromethene (BODIPY)-based photosensitizers for photodynamic therapy'. Together they form a unique fingerprint.

Cite this