A 32-to-4% sucrose devaluation leads to suppression of consummatory behavior relative to unshifted 4% sucrose controls. This is accompanied by an emotional response inducing memory consolidation. Expression levels of phosphorylated cyclic adenosine monophosphate response element-binding protein (pCREB, a marker of synaptic plasticity) were higher after the first devaluation session than after the second in prelimbic cortex, anterior cingulate cortex, and dorso-medial striatum. The central nucleus of the amygdala showed a tendency to differential pCREB expression. This evidence contributes to identifying the brain circuit for one form of traumatic memory involving reward loss.
|Number of pages||5|
|State||Published - Feb 5 2015|
Bibliographical notePublisher Copyright:
© 2014 Elsevier Ireland Ltd.
- Anterior cingulate
- Consummatory successive negative contrast
- Dorsal striatum
- Memory consolidation
- Prelimbic cortex
ASJC Scopus subject areas
- Neuroscience (all)