Carbohydrate utilization by the Lyme borreliosis spirochete, Borrelia burgdorferi

Kate Von Lackum; Brian Stevenson

doi:10.1016/j.femsle.2004.12.002

Carbohydrate utilization by the Lyme borreliosis spirochete, Borrelia burgdorferi

Kate Von Lackum, Brian Stevenson

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Abstract

Growth kinetic analyses of Borrelia burgdorferi indicated that this bacterium can utilize a limited number of carbon sources for energy: the monosaccharides glucose, mannose, and N-acetylglucosamine, the disaccharides maltose and chitobiose, and glycerol. All of these carbohydrates are likely to be available to B. burgdorferi during infection of either vertebrate and arthropod hosts, enabling development of a model describing energy sources potentially used by the Lyme borreliosis spirochete during its natural infectious cycle.

Original language	English
Pages (from-to)	173-179
Number of pages	7
Journal	FEMS Microbiology Letters
Volume	243
Issue number	1
DOIs	https://doi.org/10.1016/j.femsle.2004.12.002
State	Published - Feb 1 2005

Bibliographical note

Funding Information:
These studies were supported by US Public Health Service Grants R01-AI53101 and 5T32-AI49795. We thank Jennifer Miller for advice on growth curve assays; Frank Gherardini, Kit Tilly, Rebecca Byram and Patricia Rosa for constructive discussions of biochemical pathways and B. burgdorferi biology; and Kelly Babb and Sara Bair for technical assistance.

Keywords

Borrelia burgdorferi
Carbohydrate utilization
Lyme borreliosis
Lyme disease
Spirochete

ASJC Scopus subject areas

Microbiology
Molecular Biology
Genetics

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10.1016/j.femsle.2004.12.002

Cite this

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title = "Carbohydrate utilization by the Lyme borreliosis spirochete, Borrelia burgdorferi",

abstract = "Growth kinetic analyses of Borrelia burgdorferi indicated that this bacterium can utilize a limited number of carbon sources for energy: the monosaccharides glucose, mannose, and N-acetylglucosamine, the disaccharides maltose and chitobiose, and glycerol. All of these carbohydrates are likely to be available to B. burgdorferi during infection of either vertebrate and arthropod hosts, enabling development of a model describing energy sources potentially used by the Lyme borreliosis spirochete during its natural infectious cycle.",

keywords = "Borrelia burgdorferi, Carbohydrate utilization, Lyme borreliosis, Lyme disease, Spirochete",

author = "{Von Lackum}, Kate and Brian Stevenson",

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AU - Stevenson, Brian

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AB - Growth kinetic analyses of Borrelia burgdorferi indicated that this bacterium can utilize a limited number of carbon sources for energy: the monosaccharides glucose, mannose, and N-acetylglucosamine, the disaccharides maltose and chitobiose, and glycerol. All of these carbohydrates are likely to be available to B. burgdorferi during infection of either vertebrate and arthropod hosts, enabling development of a model describing energy sources potentially used by the Lyme borreliosis spirochete during its natural infectious cycle.

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KW - Spirochete

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Carbohydrate utilization by the Lyme borreliosis spirochete, Borrelia burgdorferi

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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