Cardiac Function in Malnourished Children

Chalie Phornphatkul, Yupada Pongprot, Robert Suskind, Varghese George, George Fuchs

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


The cardiovascular status of severely malnourished children was characterized before, during, and after nutritional rehabilitation. In most children with third-degree malnutrition, cardiac mass was decreased on admission to the hospital and recovered subsequent to nutritional therapy. All children had echocardiographic and Doppler measurements indicative of impaired ventricular function which significantly improved during the course of hospitalization, as evidenced in part by the change in fractional shortening (P= 0.015), mean velocity of circumferential fiber shortening (P= 0.038), and systolic time interval (P = 0.030). We conclude that children with primary third-degree malnutrition not only have cardiac muscle wasting, but also have inherent ventricular dysfunction as the result of severe malnutrition that responds to nutritional therapy. Particular care with fluid administration is imperative in the first week of therapy, when heart function is the most compromised.

Original languageEnglish
Pages (from-to)147-154
Number of pages8
JournalClinical Pediatrics
Issue number3
StatePublished - Mar 1994

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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