Case series of therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy during extracorporeal life support

Prasad Bhandary, John M. Daniel, Sean C. Skinner, Matthew K. Bacon, Mina Hanna, John A. Bauer, Peter Giannone, Hubert O. Ballard

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Therapeutic hypothermia initiated within 6 hours of birth is currently the standard of care for the management of neonates with hypoxic-ischemic encephalopathy. Neonates undergoing therapeutic hypothermia for hypoxic-ischemic encephalopathy are also at risk for severe respiratory failure and need for extracorporeal life support. The risks and benefits of therapeutic hypothermia for hypoxic-ischemic encephalopathy during extracorporeal life support are still not well defined. We report our experience of a case series of six neonates who underwent therapeutic hypothermia for hypoxic-ischemic encephalopathy during extracorporeal life support. We also report long-term neurodevelopmental follow-up from 6 to 24 months and add to the current body of evidence regarding feasibility, clinical experience, and short-term complications.

Original languageEnglish
Pages (from-to)700-706
Number of pages7
JournalPerfusion (United Kingdom)
Volume35
Issue number7
DOIs
StatePublished - Oct 1 2020

Bibliographical note

Publisher Copyright:
© The Author(s) 2020.

Keywords

  • extracorporeal life support
  • hypoxic-ischemic encephalopathy
  • neonatal encephalopathy
  • therapeutic hypothermia

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Safety Research
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing

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