Celastrol inhibits polyglutamine aggregation and toxicity though induction of the heat shock response

Pharmacology, Toxicology and Pharmaceutical Science

• Toxicity 100%
• Shock 100%
• Polyglutamine 100%
• Celastrol 100%
• Heat Shock Protein 80%
• Disease 60%
• Protein 40%
• Sodium Dodecyl Sulfate 20%
• Transcription Factors 20%

Biochemistry, Genetics and Molecular Biology

• Heat Shock Response 100%
• Heat Shock Protein 100%
• Gene Expression 50%
• Mutant 50%
• Protein 25%
• Solubility 25%
• Protein Repeat 25%
• Protein Expression 25%
• HSF1 25%
• Sodium Dodecyl Sulfate 25%
• Transcription Factors 25%
• Miscibility 25%

Neuroscience

• Polyglutamine 100%
• Celastrol 100%
• Heat Shock Protein 80%
• Protein 40%
• Gene Expression 40%
• Transcription Factors 20%
• Sodium Dodecyl Sulfate 20%
• HSF1 20%
• Protein Expression 20%