Cellular mechanics in human blood eosinophils and leukotriene C 4 synthesis

Christopher M. Waters; Ushma Savla; Pam Kuagoolwongse; Peter H.S. Sporn

Cellular mechanics in human blood eosinophils and leukotriene C ₄ synthesis

Christopher M. Waters, Ushma Savla, Pam Kuagoolwongse, Peter H.S. Sporn

Physiology

Research output: Contribution to journal › Conference article › peer-review

Abstract

Cellular mechanics in human blood eosinophils and leukotriene C ₄ (LTC₄) synthesis were studied. The inhibition of LTC₄ synthesis was sustained for 2 hours after initial stretch treatment. It was demonstrated that the cyclic mechanical strain inhibits LTC₄ synthesis by adherent eosinophils in a frequency-dependent and relaxation time-dependent manner.

Original language	English
Pages (from-to)	635-636
Number of pages	2
Journal	American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume	50
State	Published - 2001
Event	Proceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States Duration: Jun 27 2001 → Jul 1 2001

ASJC Scopus subject areas

General Engineering

Cite this

@article{74f053742bdd4f2fbba862f5ec99eca1,

title = "Cellular mechanics in human blood eosinophils and leukotriene C 4 synthesis",

abstract = "Cellular mechanics in human blood eosinophils and leukotriene C 4 (LTC4) synthesis were studied. The inhibition of LTC4 synthesis was sustained for 2 hours after initial stretch treatment. It was demonstrated that the cyclic mechanical strain inhibits LTC4 synthesis by adherent eosinophils in a frequency-dependent and relaxation time-dependent manner.",

author = "Waters, {Christopher M.} and Ushma Savla and Pam Kuagoolwongse and Sporn, {Peter H.S.}",

year = "2001",

language = "English",

volume = "50",

pages = "635--636",

note = "Proceedings of the 2001 Bioengineering Conference ; Conference date: 27-06-2001 Through 01-07-2001",

}

TY - JOUR

T1 - Cellular mechanics in human blood eosinophils and leukotriene C 4 synthesis

AU - Waters, Christopher M.

AU - Savla, Ushma

AU - Kuagoolwongse, Pam

AU - Sporn, Peter H.S.

PY - 2001

Y1 - 2001

N2 - Cellular mechanics in human blood eosinophils and leukotriene C 4 (LTC4) synthesis were studied. The inhibition of LTC4 synthesis was sustained for 2 hours after initial stretch treatment. It was demonstrated that the cyclic mechanical strain inhibits LTC4 synthesis by adherent eosinophils in a frequency-dependent and relaxation time-dependent manner.

AB - Cellular mechanics in human blood eosinophils and leukotriene C 4 (LTC4) synthesis were studied. The inhibition of LTC4 synthesis was sustained for 2 hours after initial stretch treatment. It was demonstrated that the cyclic mechanical strain inhibits LTC4 synthesis by adherent eosinophils in a frequency-dependent and relaxation time-dependent manner.

UR - http://www.scopus.com/inward/record.url?scp=0242525104&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0242525104&partnerID=8YFLogxK

M3 - Conference article

AN - SCOPUS:0242525104

SN - 1071-6947

VL - 50

SP - 635

EP - 636

JO - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

JF - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

T2 - Proceedings of the 2001 Bioengineering Conference

Y2 - 27 June 2001 through 1 July 2001

ER -

Cellular mechanics in human blood eosinophils and leukotriene C ₄ synthesis

Abstract

ASJC Scopus subject areas

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