Central cytometabolic functional vascular coupling in health and disease

Sophiya L. Sims, Ting Hsuan Lu, Blaine E. Weiss, Ruei Lung Lin, Leopoldine B. Galopin, Nicholas A. Wright, Christopher Norris, Olivier Thibault

Research output: Contribution to journalReview articlepeer-review

Abstract

The neurovascular unit includes multiple cell types that communicate with each other on a second-by-second basis using traditional neurotransmitters and other signaling molecules, however the function of each cell or the mechanisms by which homeostasis is maintained are still unclear. Here, we review the important elements of the astro- and neurovascular unit and the modulators that contribute to the orchestration of functional hyperemia in health and disease.

Original languageEnglish
Article number47
JournalNPJ Metabolic Health and Disease
Volume3
Issue number1
DOIs
StatePublished - Dec 2025

Bibliographical note

Publisher Copyright:
© The Author(s) 2025.

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Genetics
  • Endocrinology

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