Characteristic and Functional Study of Intersex, a Gene Related to Female Fertility in Bemisia tabaci

Yating Liu, Jinjian Yang, Zhijia Huo, Shaoli Wang, Qingjun Wu, Xuguo Zhou, Wen Xie, Youjun Zhang

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


The intersex (ix) gene acts in concert with doublesex (dsx) at the end of the sex determination hierarchy to control somatic sexual differentiation in Drosophila melanogaster. Here, we report the Drosophila ix homolog in Bemisia tabaci (Btix) with differential splicing events. Four isoforms were found in B. tabaci adults, including two sex-specific transcripts (BtixF and BtixM). Knockdown of Btix had no measurable effects on female morphological phenotypes but reduced the expression of the vitellogenin gene and resulted in the production of significantly fewer eggs, a lower eclosion rate, and a shorter body size of female progeny in comparison with control females. These results increase our understanding of the genes underlying sex determination in B. tabaci and reveal a potential target for RNA interference-based pest management.

Original languageEnglish
Article number55
JournalFrontiers in Physiology
StatePublished - Feb 25 2020

Bibliographical note

Publisher Copyright:
© Copyright © 2020 Liu, Yang, Huo, Wang, Wu, Zhou, Xie and Zhang.


  • Bemisia tabaci
  • RNA interference
  • intersex
  • pest control
  • sex determination

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)


Dive into the research topics of 'Characteristic and Functional Study of Intersex, a Gene Related to Female Fertility in Bemisia tabaci'. Together they form a unique fingerprint.

Cite this