Characteristics Associated with Prolonged Length of Stay after Myomectomy for Uterine Myomas

Study Objective: To identify factors contributing to prolonged hospitalization for women undergoing myomectomy for uterine myomas. Patients: Women undergoing myomectomy for uterine myomas during 2014 to 2016 were identified by the Current Procedural Terminology code. Design: Retrospective population-based analysis of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. Setting: Data from the American College of Surgeons National Surgical Quality Improvement Project. Interventions: None. Measurements and Main Results: The primary outcome was length of stay longer than the median (1 day). Preoperative, intraoperative, and postoperative variables were examined to determine predictors for prolonged length of stay (LOS). Seven thousand five hundred thirty-one women underwent abdominal or laparoscopic myomectomy for uterine myomas. Nonwhite race (black: odds ratio [OR] = 2.25; 95% confidence interval [CI], 2.01–2.51; Asian: OR = 1.54; 95% CI, 1.27–1.85; other/unknown: OR = 2.82; 95% CI, 2.43–3.27), preoperative hematocrit <38% (OR = 1.38; 95% CI, 1.26–1.52), body mass index ≥30.1 kg/m² (OR = 1.36; 95% CI, 1.21–1.53), preoperative blood transfusion (OR = 3.70; 95% CI, 2.03–6.74), perioperative blood transfusion (OR = 6.64; 95% CI, 4.76-9.27), removal of ≥5 myomas (OR = 1.47; 95% CI, 1.28–1.70), and operative time >120 minutes (121–150 minutes: OR = 1.42; 95% CI, 1.15–1.77; 151–180 minutes: OR = 1.59; 95% CI, 1.24–2.03; ≥181 minutes: OR = 1.36; 95% CI, 1.10–1.69) predicted prolonged LOS. Laparoscopy protected against prolonged LOS (OR = 0.11; 95% CI, 0.09–0.13). Conclusions: Limited potentially modifiable perioperative factors contributing to prolonged LOS for abdominal or laparoscopic myomectomy were identified and suggest areas for targeted interventions.